major depressive disorder

Summary
Synonym
  • clinical depression
  • major depression
  • recurrent major depression
  • single major depressive episode
  • unipolar depression
Definition
A depressive disorder that is characterized by at least two weeks of loss of interest or pleasure in normally enjoyable activities or depressed mood along with additional cognitive or somatic impairments such as appetite or weight changes, sleep difficulties, psychomotor agitation or retardation, fatigue or loss of energy, diminished ability to think or concentrate, feelings of worthlessness or excessive guilt, and suicidality.
Super Class
depressive disorder
External Links
Disease Ontology
DOID:1470
Mondo Disease Ontology
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 151 - 160 of 217 in total
Gene ID Gene Symbol Description Source
9415 FADS2 fatty acid desaturase 2
9420 CYP7B1 cytochrome P450 family 7 subfamily B member 1
9524 TECR trans-2,3-enoyl-CoA reductase
9695 EDEM1 ER degradation enhancing alpha-mannosidase like protein 1
9896 FIG4 FIG4 phosphoinositide 5-phosphatase
9926 LPGAT1 lysophosphatidylglycerol acyltransferase 1
10159 ATP6AP2 ATPase H+ transporting accessory protein 2
10327 AKR1A1 aldo-keto reductase family 1 member A1
10610 ST6GALNAC2 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
10855 HPSE heparanase
Displaying 1 entry
Gene ID Gene Symbol Description Source
15558 Htr2a 5-hydroxytryptamine (serotonin) receptor 2A
Displaying 1 entry
Gene ID Gene Symbol Description Source
29595 Htr2a 5-hydroxytryptamine receptor 2A

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Last updated: August 19, 2024