major depressive disorder

Summary
Synonym
  • clinical depression
  • major depression
  • recurrent major depression
  • single major depressive episode
  • unipolar depression
Definition
A depressive disorder that is characterized by at least two weeks of loss of interest or pleasure in normally enjoyable activities or depressed mood along with additional cognitive or somatic impairments such as appetite or weight changes, sleep difficulties, psychomotor agitation or retardation, fatigue or loss of energy, diminished ability to think or concentrate, feelings of worthlessness or excessive guilt, and suicidality.
Super Class
depressive disorder
External Links
Disease Ontology
DOID:1470
Mondo Disease Ontology
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 51 - 60 of 217 in total
Gene ID Gene Symbol Description Source
1636 ACE angiotensin I converting enzyme
1646 AKR1C2 aldo-keto reductase family 1 member C2
1738 DLD dihydrolipoamide dehydrogenase
2026 ENO2 enolase 2
2053 EPHX2 epoxide hydrolase 2
2182 ACSL4 acyl-CoA synthetase long chain family member 4
2224 FDPS farnesyl diphosphate synthase
2525 FUT3 fucosyltransferase 3 (Lewis blood group)
2571 GAD1 glutamate decarboxylase 1
2572 GAD2 glutamate decarboxylase 2
Displaying 1 entry
Gene ID Gene Symbol Description Source
15558 Htr2a 5-hydroxytryptamine (serotonin) receptor 2A
Displaying 1 entry
Gene ID Gene Symbol Description Source
29595 Htr2a 5-hydroxytryptamine receptor 2A
Related Glycoprotein
Displaying entry 161 - 161 of 161 in total
UniProt ID Protein Name Source
Q9Y6A2 Cholesterol 24-hydroxylase

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