Langerhans-cell histiocytosis

Summary
Synonym
  • Histiocytosis X
  • Langerhan's cell histiocytosis
  • Langerhans cell granulomatosis
  • Letterer-Siwe disease
  • Letterer-Siwe disease involving intra-abdominal lymph nodes
  • Letterer-Siwe disease involving intrapelvic lymph nodes
  • Letterer-Siwe disease involving intrathoracic lymph nodes
  • Letterer-Siwe disease involving lymph nodes of axilla and upper limb
  • Letterer-Siwe disease involving lymph nodes of head, face and neck
  • Letterer-Siwe disease involving lymph nodes of head, face, and neck
  • Letterer-Siwe disease involving lymph nodes of inguinal region and lower limb
  • Letterer-Siwe disease involving lymph nodes of multiple sites
  • Letterer-Siwe disease involving spleen
  • Letterer-Siwe disease of intra-abdominal lymph nodes
  • Letterer-Siwe disease of intrapelvic lymph nodes
  • Letterer-Siwe disease of intrathoracic lymph nodes
  • Letterer-Siwe disease of lymph nodes of axilla and upper limb
  • Letterer-Siwe disease of lymph nodes of axilla and/or upper limb
  • Letterer-Siwe disease of lymph nodes of head, face and neck
  • Letterer-Siwe disease of lymph nodes of head, face and/or neck
  • Letterer-Siwe disease of lymph nodes of inguinal region amd/or lower limb
  • Letterer-Siwe disease of lymph nodes of inguinal region and lower limb
  • Letterer-Siwe disease of lymph nodes of inguinal region and/or lower limb
  • Letterer-Siwe disease of lymph nodes of multiple sites
  • Letterer-Siwe disease of spleen
Definition
A histiocytosis that is characterized by clonal proliferation of Langerhans cells.
Super Class
histiocytosis
External Links
Disease Ontology
DOID:2571
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
Related Genes
Displaying entries 21 - 30 of 71 in total
Gene ID Gene Symbol Description Source
1586 CYP17A1 cytochrome P450 family 17 subfamily A member 1
1591 CYP24A1 cytochrome P450 family 24 subfamily A member 1
1594 CYP27B1 cytochrome P450 family 27 subfamily B member 1
1604 CD55 CD55 molecule (Cromer blood group)
1636 ACE angiotensin I converting enzyme
1645 AKR1C1 aldo-keto reductase family 1 member C1
2053 EPHX2 epoxide hydrolase 2
2215 FCGR3B Fc gamma receptor IIIb
2220 FCN2 ficolin 2
2271 FH fumarate hydratase
Displaying 1 entry
Gene ID Gene Symbol Description Source
109880 Braf Braf transforming gene

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Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024