osteosarcoma

Summary
Synonym
  • Osteogenic sarcoma
  • Skeletal sarcoma
  • bone tissue neoplasm
  • osteoid sarcoma
Definition
A bone sarcoma that is located_in bone that has_material_basis_in cells of mesenchymal origin. It usually involves bones and less frequently extraosseous sites. It often involves the long bones (particularly distal femur, proximal tibia, and proximal humerus).
Super Class
bone sarcoma
Disease Ontology
DOID:3347
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
ORDO
OMIM
GARD
MGI genotype (from TogoID)
Related Genes
Displaying entries 11 - 19 of 19 in total
Gene ID Gene Symbol Description Source
4436 MSH2 mutS homolog 2
5176 SERPINF1 serpin family F member 1
5787 PTPRB protein tyrosine phosphatase receptor type B
5925 RB1 RB transcriptional corepressor 1
7157 TP53 tumor protein p53
7852 CXCR4 C-X-C motif chemokine receptor 4
9590 AKAP12 A-kinase anchoring protein 12
11200 CHEK2 checkpoint kinase 2
30008 EFEMP2 EGF containing fibulin extracellular matrix protein 2
Displaying entries 11 - 14 of 14 in total
Gene ID Gene Symbol Description Source
58859 Efemp2 epidermal growth factor-containing fibulin-like extracellular matrix protein 2
69151 Lzic leucine zipper and CTNNBIP1 domain containing
71702 Cdc5l cell division cycle 5-like
83397 Akap12 A kinase anchor protein 12
Displaying all 3 entries
Gene ID Gene Symbol Description Source
24842 Tp53 tumor protein p53
60628 Cxcr4 C-X-C motif chemokine receptor 4
63864 Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10
Displaying 1 entry
Gene ID Gene Symbol Description Source
32115 Ptp10D Protein tyrosine phosphatase 10D
Displaying all 3 entries
Gene ID Gene Symbol Description Source Organism
380373 cxcr4.S C-X-C motif chemokine receptor 4 S homeolog Xenopus laevis (African clawed frog)
100038176 cxcr4 C-X-C motif chemokine receptor 4 Xenopus tropicalis (tropical clawed frog)
100192360 cxcr4.L C-X-C motif chemokine receptor 4 L homeolog Xenopus laevis (African clawed frog)
Displaying all 2 entries
Gene ID Gene Symbol Description Source
174437 dep-1 Receptor-type tyrosine-protein phosphatase dep-1
180622 ddr-2 Discoidin domain-containing receptor tyrosine kinase B
Displaying 1 entry
Gene ID Gene Symbol Description Source
852092 PHO8 alkaline phosphatase PHO8

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Last updated: December 9, 2024