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Standards Ontologies Notations
type 1 diabetes mellitus

Summary
Synonym
  • IDDM
  • insulin-dependent diabetes mellitus
  • type I diabetes mellitus
Definition
A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.
Super Class
autoimmune disease of endocrine system diabetes mellitus
Disease Ontology
DOID:9744
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
MGI genotype (from TogoID)
Related Genes
Displaying entries 81 - 90 of 133 in total
Gene ID Gene Symbol Description Source
5327 PLAT plasminogen activator, tissue type
5444 PON1 paraoxonase 1
5551 PRF1 perforin 1
5644 PRSS1 serine protease 1
5798 PTPRN protein tyrosine phosphatase receptor type N
5799 PTPRN2 protein tyrosine phosphatase receptor type N2
5967 REG1A regenerating family member 1 alpha
6347 CCL2 C-C motif chemokine ligand 2
6352 CCL5 C-C motif chemokine ligand 5
6356 CCL11 C-C motif chemokine ligand 11
Displaying entries 51 - 60 of 102 in total
Gene ID Gene Symbol Description Source
16175 Il1a interleukin 1 alpha
16177 Il1r1 interleukin 1 receptor, type I
16181 Il1rn interleukin 1 receptor antagonist
16183 Il2 interleukin 2
16184 Il2ra interleukin 2 receptor, alpha chain
16189 Il4 interleukin 4
16333 Ins1 insulin I
16334 Ins2 insulin II
16440 Itpr3 inositol 1,4,5-triphosphate receptor 3
16992 Lta lymphotoxin A
Displaying entries 1 - 10 of 61 in total
Gene ID Gene Symbol Description Source
24221 Avp arginine vasopressin
24232 C3 complement C3
24310 Ace angiotensin I converting enzyme
24375 Fuca1 alpha-L-fucosidase 1
24377 G6pd glucose-6-phosphate dehydrogenase
24464 Hp haptoglobin
24476 Iapp islet amyloid polypeptide
24483 Igf2 insulin-like growth factor 2
24484 Igfbp3 insulin-like growth factor binding protein 3
24493 Il1a interleukin 1 alpha
Displaying entries 1 - 10 of 43 in total
Gene ID Gene Symbol Description Source
31364 Fas2 Fasciclin 2
31926 Idgf4 Imaginal disc growth factor 4
32974 Zw Zwischenferment
34091 Spn28Dc Serpin 28Dc
34189 Acer Angiotensin-converting enzyme-related
34805 Ance Angiotensin converting enzyme
34978 Idgf1 Imaginal disc growth factor 1
34979 Idgf2 Imaginal disc growth factor 2
34981 Idgf3 Imaginal disc growth factor 3
35105 Ugt301D1 UDP-glycosyltransferase family 301 member D1
Displaying all 7 entries
Gene ID Gene Symbol Description Source
30262 ins preproinsulin
114549 ache acetylcholinesterase (Yt blood group)
406731 ugt1ab UDP glucuronosyltransferase 1 family a, b
447803 pon1 paraoxonase 1
560951 xylt1 xylosyltransferase I
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
100384891 ugt1a7 UDP glucuronosyltransferase 1 family, polypeptide A7
Displaying entries 1 - 10 of 12 in total
Gene ID Gene Symbol Description Source Organism
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
397761 ncam1.S neural cell adhesion molecule 1 S homeolog Xenopus laevis (African clawed frog)
397762 ncam1.L neural cell adhesion molecule 1 L homeolog Xenopus laevis (African clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
444363 xylt1.L xylosyltransferase I L homeolog Xenopus laevis (African clawed frog)
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
100135191 ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 Xenopus tropicalis (tropical clawed frog)
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
100145490 xylt1 xylosyltransferase I Xenopus tropicalis (tropical clawed frog)
Displaying entries 21 - 29 of 29 in total
Gene ID Gene Symbol Description Source
181178 gpx-5 Glutathione peroxidase
181334 pek-1 Eukaryotic translation initiation factor 2-alpha kinase pek-1
181706 ace-1 Acetylcholinesterase 1
182513 gpx-3 Glutathione peroxidase 3
187297 poml-1 PON (paraoxonase) and MEC-6 Like
188252 lev-9 Protein lev-9
189173 W03G11.3 Putative alpha-L-fucosidase
190099 sqv-6 Xylosyltransferase sqv-6;protein xylosyltransferase
191766 smf-2 NRAMP-like transporter smf-2
Displaying all 4 entries
Gene ID Gene Symbol Description Source
850721 SMF3 putative divalent metal ion transporter SMF3
850886 ATG26 sterol 3-beta-glucosyltransferase
851977 CTS2 putative chitinase
855480 ZWF1 glucose-6-phosphate dehydrogenase
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024