obesity

Summary
Definition
An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.
Super Class
overnutrition
Related Genes
Displaying entries 1 - 10 of 333 in total
Gene ID Gene Symbol Description Source
28 ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase
31 ACACA acetyl-CoA carboxylase alpha
32 ACACB acetyl-CoA carboxylase beta
34 ACADM acyl-CoA dehydrogenase medium chain
37 ACADVL acyl-CoA dehydrogenase very long chain
38 ACAT1 acetyl-CoA acetyltransferase 1
43 ACHE acetylcholinesterase (Yt blood group)
47 ACLY ATP citrate lyase
51 ACOX1 acyl-CoA oxidase 1
125 ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
Displaying entries 31 - 36 of 36 in total
Gene ID Gene Symbol Description Source
59027 Nampt nicotinamide phosphoribosyltransferase
68054 Serpina12 serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
72774 Neil1 nei endonuclease VIII-like 1 (E. coli)
103988 Gck glucokinase
105787 Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit
230796 Wdtc1 WD and tetratricopeptide repeats 1
Displaying entries 1 - 10 of 27 in total
Gene ID Gene Symbol Description Source
24267 Comt catechol-O-methyltransferase
24377 G6pd glucose-6-phosphate dehydrogenase
24383 Gapdh glyceraldehyde-3-phosphate dehydrogenase
24385 Gck glucokinase
24536 Lepr leptin receptor
24577 Myc MYC proto-oncogene, bHLH transcription factor
24835 Tnf tumor necrosis factor
25058 Hk1 hexokinase 1
25059 Hk2 hexokinase 2
25233 Akt2 AKT serine/threonine kinase 2
Displaying entry 11 - 11 of 11 in total
Gene ID Gene Symbol Description Source
117364 Hex-t1 Hexokinase testis 1
Displaying 1 entry
Gene ID Gene Symbol Description Source
317743 gapdh glyceraldehyde-3-phosphate dehydrogenase
Displaying all 4 entries
Gene ID Gene Symbol Description Source
174578 gpd-4 Glyceraldehyde-3-phosphate dehydrogenase 4
174603 gpd-1 Glyceraldehyde-3-phosphate dehydrogenase 1
178046 gspd-1 Glucose-6-phosphate 1-dehydrogenase
180601 gpd-3 Glyceraldehyde-3-phosphate dehydrogenase 3
Displaying entry 11 - 11 of 11 in total
Gene ID Gene Symbol Description Source
856294 RHO1 Rho family GTPase RHO1
The Human Phenotype Ontology
Displaying all 5 entries
HPO ID HPO Term
HP:0000007 Autosomal recessive inheritance
HP:0001513 Obesity
HP:0000006 Autosomal dominant inheritance
HP:0010982 Polygenic inheritance
HP:0012340 Decreased resting energy expenditure
Displaying all 2 entries
Gene ID Gene Symbol Description
9672 SDC3 syndecan 3
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1

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Acknowledgements

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Last updated: August 19, 2024