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ras homolog gene family, member Ab

Summary

Gene Symbol

rhoab

Organism

Danio rerio (zebrafish)

External Links

NCBI Gene

100006041

PubChem

100006041

Alliance of Genome Resources

ZFIN:ZDB-GENE-040322-2

Annotation

Keyword

Cell membrane
GTP-binding
Glycoprotein
Methylation
Prenylation
Proteomics identification
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q6DHM9
A0A8M9QIE1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
actin filament organization	IBA
signal transduction	IBA
small GTPase mediated signal transduction	IEA
Rho protein signal transduction	IMP	17873909
Wnt signaling pathway	IGI	16019189

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization [inference]

establishment of spindle localization [inference]

establishment of mitotic spindle localization

microtubule cytoskeleton organization involved in mitosis [inference]

establishment of mitotic spindle localization

signal transduction

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

intracellular signal transduction [inference]

small GTPase mediated signal transduction

Ras protein signal transduction [inference]

Rho protein signal transduction

cell cycle process [inference]

spindle localization [inference]

establishment of spindle localization [inference]

establishment of mitotic spindle localization

mitotic cell cycle process [inference]

microtubule cytoskeleton organization involved in mitosis [inference]

establishment of mitotic spindle localization

actin filament-based process [inference]

actin cytoskeleton organization [inference]

actomyosin structure organization [inference]

stress fiber assembly

cell motility [inference]

cell migration

ameboidal-type cell migration [inference]

cell migration involved in gastrulation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization [inference]

establishment of spindle localization [inference]

establishment of mitotic spindle localization

microtubule cytoskeleton organization involved in mitosis [inference]

establishment of mitotic spindle localization

actin cytoskeleton organization [inference]

actomyosin structure organization [inference]

stress fiber assembly

cellular component assembly [inference]

actin filament bundle assembly [inference]

contractile actin filament bundle assembly [inference]

stress fiber assembly

supramolecular fiber organization [inference]

actin filament organization

actin filament bundle organization [inference]

actin filament bundle assembly [inference]

contractile actin filament bundle assembly [inference]

stress fiber assembly

developmental process [inference]

anatomical structure morphogenesis [inference]

post-anal tail morphogenesis

anatomical structure development [inference]

otolith development

localization [inference]

establishment of localization [inference]

establishment of localization in cell [inference]

establishment of spindle localization [inference]

establishment of mitotic spindle localization

establishment of organelle localization [inference]

establishment of spindle localization [inference]

establishment of mitotic spindle localization

organelle localization [inference]

spindle localization [inference]

establishment of spindle localization [inference]

establishment of mitotic spindle localization

establishment of organelle localization [inference]

establishment of spindle localization [inference]

establishment of mitotic spindle localization

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

regulation of Rho protein signal transduction

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

regulation of Rho protein signal transduction

regulation of cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

intracellular signal transduction [inference]

small GTPase mediated signal transduction

Ras protein signal transduction [inference]

Rho protein signal transduction

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

regulation of Rho protein signal transduction

regulation of actin filament-based process [inference]

regulation of actin cytoskeleton organization

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

regulation of cytoskeleton organization [inference]

regulation of actin cytoskeleton organization

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GO Term	Evidence Code	PMID
cytosol	IBA
plasma membrane	IBA
plasma membrane	IEA
membrane	IEA
cleavage furrow

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

membrane

plasma membrane

plasma membrane region [inference]

cleavage furrow

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

neuron spine [inference]

dendritic spine

postsynapse [inference]

dendritic spine

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
nucleotide binding	IEA
GTPase activity	IBA
GTPase activity	IEA
GTP binding	IBA
GTP binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

GTPase activity

binding [inference]

protein binding [inference]

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

GTP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

GTPase

Functional Category

T: Signal transduction mechanisms
U: Intracellular trafficking, secretion, and vesicular transport

Displaying **all 4** entries
Gene Ontology
GTP binding
nucleotide binding
protein kinase binding
small GTPase-mediated signal transduction

Displaying **all 4** entries
InterPro
P-loop containing nucleoside triphosphate hydrolase
Small GTP-binding protein domain
Small GTPase Rho
Small GTPase

Ortholog

Displaying entries **1 - 10** of 25 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	387	Xenbase:XB-GENE-489222
Saccharomyces cerevisiae S288C	388	SGD:S000006369
Saccharomyces cerevisiae S288C	389	SGD:S000006369
Saccharomyces cerevisiae S288C	406411	SGD:S000006369
Saccharomyces cerevisiae S288C	406659	SGD:S000006369
Saccharomyces cerevisiae S288C	436718	SGD:S000006369
Xenopus tropicalis	856294	Xenbase:XB-GENE-489222
Xenopus tropicalis	100006041	Xenbase:XB-GENE-489222
Ictalurus punctatus	100528424		ICTPU30033
Astyanax mexicanus	103027457		ASTMX20286