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G protein-coupled receptor 161

Summary

Gene Symbol

gpr161

Organism

Xenopus tropicalis (tropical clawed frog)

External Links

NCBI Gene

100170613

PubChem

100170613

Alliance of Genome Resources

Xenbase:XB-GENE-1003408

Annotation

Keyword

Cell membrane
Cilium
Developmental protein
Disulfide bond
G-protein coupled receptor
Glycoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
B3DM66
A0A8J1J4L7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
G protein-coupled receptor signaling pathway	IBA
G protein-coupled receptor signaling pathway	IEA
adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISS
negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning	ISS

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
plasma membrane	IEA
cilium	ISS
cilium	IEA
membrane	IEA
recycling endosome	ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

ciliary membrane

plasma membrane region [inference]

cell projection membrane [inference]

ciliary membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium

organelle [inference]

membrane-bounded organelle [inference]

cilium

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

recycling endosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

recycling endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

recycling endosome

Displaying **all 3** entries
GO Term	Evidence Code	PMID
G protein-coupled receptor activity	ISS
G protein-coupled receptor activity	IBA
G protein-coupled receptor activity	IEA

GO Hierarchy

molecular function

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

G-protein coupled receptor

Functional Category

E: Amino acid transport and metabolism
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources
Danio rerio	23432	ZFIN:ZDB-GENE-120215-39
Danio rerio	240888	ZFIN:ZDB-GENE-030616-58
Danio rerio	368421	ZFIN:ZDB-GENE-030616-58
Danio rerio	100170613	ZFIN:ZDB-GENE-120215-39