GlyCosmos Portal

Submissions

G protein-coupled receptor 161b

Summary

Gene Symbol

gpr161b

Organism

Danio rerio (zebrafish)

External Links

NCBI Gene

368421

PubChem

368421

Alliance of Genome Resources

ZFIN:ZDB-GENE-030616-58

Annotation

Keyword

Cell membrane
Cilium
Developmental protein
Disulfide bond
G-protein coupled receptor
Glycoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q90X46

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
signal transduction	IEA
G protein-coupled receptor signaling pathway	IBA
G protein-coupled receptor signaling pathway	IEA
adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISS
determination of left/right symmetry	IMP	18755178

GO Hierarchy

biological process

cellular process [inference]

signal transduction

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

multicellular organismal process [inference]

pattern specification process [inference]

specification of symmetry [inference]

determination of bilateral symmetry [inference]

determination of left/right symmetry

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

regulation of localization [inference]

regulation of transport [inference]

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of calcium ion transport

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

regulation of cellular process [inference]

signal transduction

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Displaying entries **1 - 5** of 8 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
plasma membrane	IEA
cilium	ISS
cilium	IEA
membrane	IEA
cell projection	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

ciliary membrane

plasma membrane region [inference]

cell projection membrane [inference]

ciliary membrane

cell projection

plasma membrane bounded cell projection [inference]

cilium

organelle [inference]

membrane-bounded organelle [inference]

cilium

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

recycling endosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

recycling endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

recycling endosome

Displaying **all 3** entries
GO Term	Evidence Code	PMID
G protein-coupled receptor activity	ISS
G protein-coupled receptor activity	IBA
G protein-coupled receptor activity	IEA

GO Hierarchy

molecular function

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

G-protein coupled receptor

Functional Category

E: Amino acid transport and metabolism
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
non-motile cilium	PMID:33531430

Ortholog

Displaying entries **1 - 10** of 82 in total

1

2

3

4

5

…

Next ›

Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	23432	Xenbase:XB-GENE-1003408	HUMAN53473
Mus musculus	240888	Xenbase:XB-GENE-1003408	MOUSE29333
Rattus norvegicus	289180		RATNO07610
Xenopus tropicalis	368421	Xenbase:XB-GENE-1003408
Canis lupus familiaris	490358		CANLF17285
Macaca mulatta	698934		MACMU22790
Pan troglodytes	747609		PANTR22949
Bos taurus	768006		BOVIN25413
Monodelphis domestica	100018613		MONDO09737
Ornithorhynchus anatinus	100083316		ORNAN07329