GlyCosmos Portal

Annotation

Keyword

ATP-binding
Endoplasmic reticulum
Glycoprotein
Hydrolase
Magnesium
Manganese
Nucleotidyltransferase
Reference proteome
Repeat
Signal-anchor
TPR repeat
Transmembrane helix
Unfolded protein response

Proteins

Displaying **all 2** entries
UniProt	Protein Name
B4F6I5	AMPylator FICD De-AMPylase FICD FIC domain-containing protein
A0A8J1J2E7	AMPylator FICD FIC domain-containing protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
response to unfolded protein	IEA
protein adenylylation	ISS
response to endoplasmic reticulum stress	ISS
protein deadenylylation	ISS
regulation of IRE1-mediated unfolded protein response	ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein nucleotidylation [inference]

protein adenylylation

protein denucleotidylation [inference]

protein deadenylylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein nucleotidylation [inference]

protein adenylylation

protein denucleotidylation [inference]

protein deadenylylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein nucleotidylation [inference]

protein adenylylation

protein denucleotidylation [inference]

protein deadenylylation

macromolecule modification [inference]

protein modification process [inference]

protein nucleotidylation [inference]

protein adenylylation

protein denucleotidylation [inference]

protein deadenylylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein nucleotidylation [inference]

protein adenylylation

protein denucleotidylation [inference]

protein deadenylylation

cellular process [inference]

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

response to topologically incorrect protein [inference]

response to unfolded protein

response to chemical [inference]

response to organic substance [inference]

response to topologically incorrect protein [inference]

response to unfolded protein

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

regulation of IRE1-mediated unfolded protein response

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

regulation of IRE1-mediated unfolded protein response

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of response to endoplasmic reticulum stress [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

regulation of IRE1-mediated unfolded protein response

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

regulation of IRE1-mediated unfolded protein response

regulation of cellular response to stress [inference]

regulation of response to endoplasmic reticulum stress [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

regulation of IRE1-mediated unfolded protein response

Displaying **all 4** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum	IEA
endoplasmic reticulum membrane	ISS
endoplasmic reticulum membrane	IEA
membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
ATP binding	ISS
ATP binding	IEA
nucleotidyltransferase activity	IEA
hydrolase activity	IEA
protein homodimerization activity	ISS

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

nucleotidyltransferase activity

adenylyltransferase activity [inference]

AMPylase activity

hydrolase activity

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphoric diester hydrolase activity [inference]

protein adenylylhydrolase activity

catalytic activity, acting on a protein [inference]

protein adenylylhydrolase activity

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

protein-folding chaperone binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

adenosine monophosphate-protein

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
AMPylase activity
ATP binding
nucleotide binding

Displaying **all 4** entries
InterPro
Fido domain-containing protein
Fido domain
Fido-like domain superfamily
Tetratricopeptide-like helical domain superfamily

Rhea

RHEA:54288

ATP

diphosphate

Enzyme

2.7.7.108

PMID

RHEA:58120

ATP

diphosphate

Enzyme

2.7.7.108

PMID

30270044

RHEA:54292

ATP

diphosphate

Enzyme

2.7.7.108

PMID

Ortholog

Displaying **all 6** entries
Species	Gene ID	Alliance of Genome Resources
Xenopus laevis	11153	Xenbase:XB-GENE-17333776
Danio rerio	231630	ZFIN:ZDB-GENE-030131-6588
Danio rerio	288741	ZFIN:ZDB-GENE-030131-6588
Xenopus laevis	100216031	Xenbase:XB-GENE-17333776
Xenopus laevis	108707071	Xenbase:XB-GENE-17333777
Xenopus laevis	108715564	Xenbase:XB-GENE-17333776

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements