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MIRAGE
ST3 beta-galactoside alpha-2,3-sialyltransferase 2

Summary
Gene Symbol
  • ST3GAL2
Organism
Capra hircus (goat)
NCBI Gene
102174236
KEGG Gene ID
chx:102174236
PubChem
102174236
Annotation
Keyword
  • Glycoprotein
  • Golgi apparatus
  • Reference proteome
  • Secreted
  • Signal
  • Signal-anchor
  • Transferase
  • Transmembrane helix
Proteins
Displaying 1 entry
UniProt Protein Name
A0A452FVE5
  • Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase
  • Monosialoganglioside sialyltransferase
Annotation information from UniProt.
Gene Ontology (GO)
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
sialyltransferase
Functional Category
  • E: Amino acid transport and metabolism
  • H: Coenzyme transport and metabolism
  • M: Cell wall/membrane/envelope biogenesis
Displaying all 9 entries
Gene Ontology
amide metabolic process
beta-galactoside (CMP) alpha-2,3-sialyltransferase activity
carbohydrate derivative biosynthetic process
cellular biosynthetic process
ganglioside biosynthetic process via lactosylceramide
organonitrogen compound biosynthetic process
sialylation
sialyltransferase activity
transferase activity
Displaying all 3 entries
InterPro
GT29-like superfamiliy
Glycosyl transferase family 29
Sialyltransferase
KEGG BRITE Database
Orthology
K03368
Name
beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4B) [EC:2.4.3.2 2.4.3.4]
References
Reactions
Displaying all 5 entries
KEGG Reaction Enzyme Acceptor Product
R05957
R05913
R05949
R05942
R05967
Rhea

RHEA:52380

a β-D-galactosyl-(1→3)-N-acetyl-β-D-galactosaminyl derivative + CMP-N-acetyl-β-neuraminate
an N-acetyl-α-neuraminyl-(2→3)-β-D-galactosyl-(1→3)-N-acetyl-β-D-galactosaminyl derivative + H+ + CMP
Enzyme
PMID

RHEA:21616

a β-D-galactosyl-(1→3)-N-acetyl-α-D-galactosaminyl derivative + CMP-N-acetyl-β-neuraminate
an N-acetyl-α-neuraminyl-(2→3)-β-D-galactosyl-(1→3)-N-acetyl-α-D-galactosaminyl derivative + H+ + CMP
Enzyme
PMID

RHEA:18021

CMP-N-acetyl-β-neuraminate + a ganglioside GM1 (d18:1(4E))
H+ + CMP + a ganglioside GD1a (d18:1(4E))
Enzyme
PMID
Ortholog
Displaying entries 21 - 30 of 79 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
100669779 LOXAF07452
100721162 CAVPO10893
100932061 SARHA03860
100943456 OTOGA10732
100981168 PANPA15570
101006642 PAPAN16385
101048291 SAIBB32481
101087029 FELCA32994
101114207 SHEEP04840
101130368 GORGO11297
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025