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MIRAGE
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2

Summary
Gene Symbol
  • ST6GALNAC2
Aliases
  • ST6GalNAII
  • STHM
Organism
Homo sapiens (human)
NCBI Gene
10610
GGDB ID
HGNC
10867
mRNA
map
  • 17q25.1
Protein
OMIM
KEGG Gene ID
hsa:10610
PubChem
10610
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Disulfide bond
  • Glycoprotein
  • Glycosyltransferase
  • Golgi apparatus
  • Reference proteome
  • Signal-anchor
  • Transmembrane helix
Proteins
Displaying 1 entry
UniProt Protein Name
Q9UJ37
  • GalNAc alpha-2,6-sialyltransferase II
  • ST6GalNAc II
  • SThM
  • Sialyltransferase 7B
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 6 in total
GO Term Evidence Code PMID
protein glycosylation
protein O-linked glycosylation
protein O-linked glycosylation
O-glycan processing
viral protein processing
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
Sialyltransferase
Functional Category
  • H: Coenzyme transport and metabolism
  • M: Cell wall/membrane/envelope biogenesis
  • T: Signal transduction mechanisms
Displaying all 2 entries
Gene Ontology
sialyltransferase activity
transferase activity
Displaying all 2 entries
InterPro
GT29-like superfamiliy
Glycosyl transferase family 29
GlycoGene Database (GGDB)
GGDB ID
gg057
Gene Symbol
  • ST6GALNAC2
Reactions
Displaying all 2 entries
Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
CMP-Neu5Ac
G00031MO
Ser/Thr
G56682BC
Ser/Thr
CMP-Neu5Ac
G65562ZE
Ser/Thr
G01614ZM
Ser/Thr
Displaying all 2 entries
Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
CMP-Neu5Ac
G00031MO
Ser/Thr
G56682BC
Ser/Thr
CMP-Neu5Ac
G65562ZE
Ser/Thr
G01614ZM
Ser/Thr
Displaying entry 16 - 16 of 16 in total
Donor Acceptor Reducing terminal(Acceptor) Reference
CMP-Neu5Ac
G00031MO
benzyl
Orthologous Gene
Displaying all 2 entries
Species Protein mRNA
Mus musculus NP_033206 NM_009180
Rattus norvegicus XP_221134 XM_221134
KEGG BRITE Database
Orthology
K06616
Name
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7B) [EC:2.4.3.3]
References
Reactions
Displaying all 2 entries
KEGG Reaction Enzyme Acceptor Product
R12704
R05914
Rhea

RHEA:11136

a β-D-galactosyl-(1→3)-N-acetyl-α-D-galactosaminyl derivative + CMP-N-acetyl-β-neuraminate
a β-D-galactosyl-(1→3)-[N-acetyl-α-neuraminyl-(2→6)]-N-acetyl-α-D-galactosaminyl derivative + H+ + CMP
Enzyme
PMID
Ortholog
Displaying entries 31 - 40 of 58 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
103345771 RABIT16955
103732780 NANGA08429
103819877 SERCA15687
104681267 RHIRO00724
105469208 MACNE15278
105543150 MANLE00219
105577679 CERAT22985
105718090 AOTNA08550
105824723 PROCO09795
106001296 DIPOR03918
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025