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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
PPARG coactivator 1 alpha
Summary
- Gene Symbol
-
- PPARGC1A
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Activator
- Alternative promoter usage
- Alternative splicing
- Biological rhythms
- Cytoplasm
- Nucleus
- Phosphoprotein
- RNA-binding
- Reference proteome
- Transcription regulation
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9UBK2 |
|
Gene Ontology (GO)
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| transcription coregulator activity | ||
| nuclear receptor binding | ||
| transcription coactivator activity | ||
| sequence-specific DNA binding | ||
| chromatin DNA binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Peroxisome proliferator-activated receptor gamma, coactivator
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- K: Transcription
- T: Signal transduction mechanisms
| InterPro |
|---|
| Nucleotide-binding alpha-beta plait domain superfamily |
| PGC-1 |
| RNA recognition motif domain |
| RNA-binding domain superfamily |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1909 | melanoma | |
| DOID:0050328 | congenital hypothyroidism | |
| DOID:0050700 | cardiomyopathy | |
| DOID:0050855 | renal fibrosis | |
| DOID:0060180 | colitis | |
| DOID:0060611 | abdominal obesity-metabolic syndrome | |
| DOID:0080208 | metabolic dysfunction-associated steatotic liver disease | |
| DOID:10376 | amblyopia | |
| DOID:10652 | Alzheimer's disease | |
| DOID:1074 | kidney failure |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 118318884 | SCOMX20742 | |||
| 118895621 | BALMU28292 | |||
| 122218573 | PANLE27894 | |||
| 123775818 | URSAM17315 | |||
| 129034980 | 9600_0:001445 |
