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FAT atypical cadherin 3

Summary

Gene Symbol

FAT3

Organism

Homo sapiens (human)

External Links

NCBI Gene

120114

PubChem

120114

Alliance of Genome Resources

HGNC:23112

Annotation

Keyword

Alternative splicing
Calcium
Cell adhesion
Developmental protein
Disulfide bond
EGF-like domain
Glycoprotein
Methylation
Proteomics identification
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8TDW7	Cadherin family member 15 FAT tumor suppressor homolog 3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
homophilic cell adhesion via plasma membrane adhesion molecules	IEA
retina layer formation	IEA
dendrite development	IEA
cell morphogenesis involved in neuron differentiation	IEA
cell-cell adhesion	IBA

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

homophilic cell adhesion via plasma membrane adhesion molecules

cell motility [inference]

cell migration [inference]

neuron migration [inference]

interneuron migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

dendrite development

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis [inference]

cell morphogenesis involved in neuron differentiation

anatomical structure formation involved in morphogenesis [inference]

retina layer formation

anatomical structure development [inference]

dendrite development

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of dendrite development

negative regulation of developmental process [inference]

negative regulation of dendrite development

regulation of developmental process [inference]

regulation of dendrite development [inference]

negative regulation of dendrite development

negative regulation of developmental process [inference]

negative regulation of dendrite development

regulation of cellular process [inference]

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of dendrite development

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of dendrite development

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

negative regulation of neuron projection development [inference]

negative regulation of dendrite development

regulation of dendrite development [inference]

negative regulation of dendrite development

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of dendrite development

Displaying **all 2** entries
GO Term	Evidence Code	PMID
plasma membrane	IEA
dendrite	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

Displaying 1 entry
GO Term	Evidence Code	PMID
calcium ion binding	IEA

GO Hierarchy

molecular function

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Protocadherin Fat

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis

Displaying **all 3** entries
Gene Ontology
cadherin binding
calcium ion binding
homophilic cell adhesion via plasma membrane adhesion molecules

Displaying **all 8** entries
InterPro
Cadherin conserved site
Cadherin-like superfamily
Cadherin-like
Cadherin
Concanavalin A-like lectin/glucanase domain superfamily
EGF-like calcium-binding domain
EGF-like domain
Laminin G domain

Ortholog

Displaying entries **1 - 10** of 76 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	2195	FB:FBgn0261574
Drosophila melanogaster	2196	FB:FBgn0261574
Drosophila melanogaster	14107	FB:FBgn0261574
Xenopus tropicalis	40191	Xenbase:XB-GENE-979369
Drosophila melanogaster	65048	FB:FBgn0261574
Xenopus tropicalis	120114	Xenbase:XB-GENE-979369
Xenopus tropicalis	175590	Xenbase:XB-GENE-979369
Rattus norvegicus	191571	Xenbase:XB-GENE-979369	RATNO41393
Drosophila melanogaster	245827	FB:FBgn0261574
Mus musculus	270120	Xenbase:XB-GENE-979369	MOUSE62143