GlyCosmos Portal

Submissions

TraB domain containing 2A

Summary

Gene Symbol

TRABD2A

Organism

Homo sapiens (human)

External Links

NCBI Gene

129293

PubChem

129293

Alliance of Genome Resources

HGNC:27013

Annotation

Keyword

Alternative splicing
Cell membrane
Glycoprotein
Metal-binding
Metalloprotease
Proteomics identification
Reference proteome
Signal
Transmembrane helix
Wnt signaling pathway

Proteins

Displaying **all 2** entries
UniProt	Protein Name
C9IYB5	TRAB domain-containing protein 2
Q86V40	TRAB domain-containing protein 2A

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
proteolysis	IDA	22726442
Wnt signaling pathway	IEA
negative regulation of Wnt signaling pathway	IDA	22726442
positive regulation of protein-containing complex assembly	ISS	22726442
head development	ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

developmental process [inference]

anatomical structure development [inference]

head development

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein oxidation

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein oxidation

regulation of nitrogen compound metabolic process [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein oxidation

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein oxidation

regulation of protein oxidation [inference]

positive regulation of protein oxidation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein oxidation

regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein oxidation

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein oxidation

regulation of protein oxidation [inference]

positive regulation of protein oxidation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein oxidation

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein oxidation

regulation of protein oxidation [inference]

positive regulation of protein oxidation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein oxidation

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

negative regulation of Wnt signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein oxidation

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein oxidation

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

negative regulation of Wnt signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

negative regulation of Wnt signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

regulation of cellular component biogenesis [inference]

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

regulation of cellular component organization [inference]

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly

Displaying **all 3** entries
GO Term	Evidence Code	PMID
plasma membrane	IDA	22726442
membrane	IBA
organelle membrane	IDA	22726442

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

Displaying entries **1 - 5** of 6 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
endopeptidase activity	IDA	22726442
metalloendopeptidase activity	ISS	22726442
metalloendopeptidase activity	IDA	22726442
metalloendopeptidase activity	IBA
Wnt-protein binding	IDA	22726442

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity

metalloendopeptidase activity

metallopeptidase activity [inference]

metalloendopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity

metalloendopeptidase activity

metallopeptidase activity [inference]

metalloendopeptidase activity

binding [inference]

protein binding [inference]

Wnt-protein binding

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Metalloprotease TIKI1

Functional Category

G: Carbohydrate transport and metabolism
J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 5** entries
Gene Ontology
hydrolase activity
metal ion binding
metalloendopeptidase activity
metallopeptidase activity
proteolysis

Displaying **all 2** entries
InterPro
Protease TIKI1/2-like
TraB/PrgY/GumN family

Ortholog

Displaying entries **1 - 10** of 53 in total

1

2

3

4

5

6

Next ›

Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	129293	Xenbase:XB-GENE-6050964
Xenopus tropicalis	181571	Xenbase:XB-GENE-6050964
Caenorhabditis elegans	388630	WB:WBGene00007351
Pan troglodytes	459355		PANTR28030
Canis lupus familiaris	483086		CANLF05183
Danio rerio	564021	Xenbase:XB-GENE-6050964	DANRE37268
Caenorhabditis elegans	566028	WB:WBGene00007351
Danio rerio	666048	ZFIN:ZDB-GENE-030131-4053
Macaca mulatta	694038		MACMU08197
Equus caballus	100067515		HORSE09557