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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
histocompatibility 2, class II antigen A, beta 1
Summary
- Gene Symbol
-
- H2-Ab1
- Organism
- Mus musculus (house mouse)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of alpha-beta T cell activation |
|
|
| antigen processing and presentation of exogenous peptide antigen via MHC class II | ||
| positive regulation of immune response | ||
| positive regulation of T-helper 1 type immune response |
|
|
| B cell affinity maturation |
|
GO Hierarchy
biological process
immune system process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| protein-containing complex binding | ||
| MHC class II protein complex binding | ||
| toxic substance binding |
|
|
| protein antigen binding |
|
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- HLA class II histocompatibility antigen, DO beta chain-like
- Functional Category
-
- E: Amino acid transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
| Gene Ontology |
|---|
| immune response |
| InterPro |
|---|
| Immunoglobulin C1-set |
| Immunoglobulin-like domain superfamily |
| Immunoglobulin-like domain |
| Immunoglobulin-like fold |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0040091 | autoimmune pancreatitis | |
| DOID:0050012 | chikungunya | |
| DOID:0050168 | autoimmune polyendocrine syndrome type 2 | |
| DOID:0050185 | erythema multiforme | |
| DOID:0050426 | Stevens-Johnson syndrome | |
| DOID:0050748 | marginal zone lymphoma | |
| DOID:0050784 | primary progressive multiple sclerosis | |
| DOID:0050827 | rheumatic heart disease | |
| DOID:0050840 | cervical dystonia | |
| DOID:0060025 | immunoglobulin alpha deficiency |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 3119 | HGNC:4944 | HUMAN84218 | ||
| 3120 | HGNC:4945 | |||
| 24738 | RGD:3467 | |||
| 24976 | RGD:3469 | |||
| 30762 | ZFIN:ZDB-GENE-980526-200 | DANRE42489 | ||
| 309622 | 10116_1:0053e8 | |||
| 326022 | ZFIN:ZDB-GENE-030131-4747 | |||
| 368615 | ZFIN:ZDB-GENE-030616-319 | DANRE43735 | ||
| 368703 | ZFIN:ZDB-GENE-030616-99 | DANRE42448 | ||
| 368846 | ZFIN:ZDB-GENE-030616-396 |
