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deleted in malignant brain tumors 1

Summary

Gene Symbol

Dmbt1

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

170568

PubChem

170568

Alliance of Genome Resources

RGD:61984

Annotation

Keyword

Alternative splicing
Cytoplasmic vesicle
Developmental protein
Differentiation
Direct protein sequencing
Disulfide bond
Glycoprotein
Phosphoprotein
Protein transport
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8CIZ5	Ebnerin Hensin Pancrin

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
receptor-mediated endocytosis	ISO
defense response to Gram-negative bacterium	ISO ISS
defense response	IBA
inner cell mass cell proliferation	ISO
defense response to Gram-positive bacterium	ISO ISS

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

humoral immune response [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

cellular process [inference]

cell population proliferation [inference]

inner cell mass cell proliferation

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis

cellular developmental process [inference]

cell differentiation

epithelial cell differentiation [inference]

columnar/cuboidal epithelial cell differentiation

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

developmental process [inference]

anatomical structure development [inference]

blastocyst development

regeneration [inference]

tissue regeneration

cellular developmental process [inference]

cell differentiation

epithelial cell differentiation [inference]

columnar/cuboidal epithelial cell differentiation

growth [inference]

developmental growth [inference]

tissue regeneration

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium

defense response to bacterium [inference]

defense response to other organism [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

defense response to bacterium [inference]

response to stimulus [inference]

response to stress [inference]

defense response

defense response to other organism [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

defense response to bacterium [inference]

immune response [inference]

humoral immune response [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium

defense response to bacterium [inference]

defense response to other organism [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

defense response to bacterium [inference]

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium

defense response to bacterium [inference]

defense response to other organism [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

defense response to bacterium [inference]

response to endogenous stimulus [inference]

response to hormone [inference]

response to estrogen

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

response to estrogen

response to organic cyclic compound [inference]

response to biphenyl

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis

organic substance transport [inference]

protein transport

nitrogen compound transport [inference]

protein transport

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis

establishment of protein localization [inference]

protein transport

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial cell differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial cell differentiation

regulation of developmental process [inference]

regulation of cell differentiation [inference]

regulation of epithelial cell differentiation [inference]

positive regulation of epithelial cell differentiation

positive regulation of cell differentiation [inference]

positive regulation of epithelial cell differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial cell differentiation

regulation of multicellular organismal development [inference]

regulation of epithelial cell differentiation [inference]

positive regulation of epithelial cell differentiation

regulation of cellular process [inference]

regulation of cell differentiation [inference]

regulation of epithelial cell differentiation [inference]

positive regulation of epithelial cell differentiation

positive regulation of cell differentiation [inference]

positive regulation of epithelial cell differentiation

positive regulation of cellular process [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial cell differentiation

regulation of multicellular organismal process [inference]

regulation of multicellular organismal development [inference]

regulation of epithelial cell differentiation [inference]

positive regulation of epithelial cell differentiation

Displaying entries **6 - 9** of 9 in total

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GO Term	Evidence Code	PMID
zymogen granule membrane	ISO ISS
extracellular space	ISO
cytoplasm	ISO
phagocytic vesicle membrane	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

transport vesicle membrane

endocytic vesicle membrane [inference]

phagocytic vesicle membrane

secretory granule membrane [inference]

zymogen granule membrane

bounding membrane of organelle [inference]

transport vesicle membrane

endocytic vesicle membrane [inference]

phagocytic vesicle membrane

secretory granule membrane [inference]

zymogen granule membrane

external encapsulating structure [inference]

extracellular matrix

collagen-containing extracellular matrix

Displaying entries **6 - 7** of 7 in total

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GO Term	Evidence Code	PMID
heparan sulfate binding	ISO
lipopolysaccharide binding	ISO

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

enzyme binding [inference]

zymogen binding

lipid binding [inference]

lipopolysaccharide binding

small molecule binding [inference]

organic acid binding [inference]

carboxylic acid binding [inference]

heparan sulfate binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

heparan sulfate binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding

carbohydrate derivative binding [inference]

lipopolysaccharide binding

glycosaminoglycan binding [inference]

heparan sulfate binding

lipoteichoic acid binding

sulfur compound binding [inference]

heparan sulfate binding

cargo receptor activity [inference]

scavenger receptor activity

molecular transducer activity [inference]

signaling receptor activity [inference]

pattern recognition receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

deleted in malignant brain tumors 1 protein

Functional Category

J: Translation, ribosomal structure and biogenesis
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
cell differentiation

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
collagen-containing extracellular matrix	PMID:11121438

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0050771	pheochromocytoma	Alliance of Genome Resources
DOID:3068	glioblastoma	Alliance of Genome Resources

Ortholog

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	1755		HGNC:2926	HUMAN03254
Mus musculus	12945	10090_1:00249f	MGI:106210	MOUSE55586
Pan troglodytes	466221			PANTR01724
Danio rerio	555768		ZFIN:ZDB-GENE-131119-30
Xenopus tropicalis	100216258		Xenbase:XB-GENE-6000361
Cricetulus griseus	100763251	10029_0:002116
Pan paniscus	100975652			PANPA05654
Jaculus jaculus	101616931	51337_0:000129
Heterocephalus glaber	101702699	10181_0:0008e0
Mesocricetus auratus	101836403	10036_0:00068e