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mannoside acetylglucosaminyltransferase 3

Summary

Gene Symbol

Mgat3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

17309

KEGG Gene ID

mmu:17309

PubChem

17309

Alliance of Genome Resources

MGI:104532

Annotation

Keyword

Proteomics identification
Reference proteome
Transferase

Proteins

Displaying 1 entry
UniProt	Protein Name
Q5RKT9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
regulation of cell migration	ISO ISS
N-acetylglucosamine metabolic process	IBA IDA	24619415
negative regulation of lysosomal protein catabolic process	IMP	25592972 26467158
protein localization to early endosome	IMP	25592972
cellular response to oxidative stress	IMP	26467158

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

peptide metabolic process [inference]

amyloid-beta metabolic process

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

amyloid-beta metabolic process

protein metabolic process [inference]

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

primary metabolic process [inference]

protein metabolic process [inference]

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

protein metabolic process [inference]

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

carbohydrate derivative metabolic process [inference]

amino sugar metabolic process [inference]

glucosamine-containing compound metabolic process [inference]

N-acetylglucosamine metabolic process

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

amyloid-beta metabolic process

protein metabolic process [inference]

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

cellular process [inference]

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization

protein localization to organelle [inference]

protein localization to endosome [inference]

protein localization to early endosome

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition

response to stimulus [inference]

response to stress [inference]

response to oxidative stress [inference]

cellular response to oxidative stress

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

response to chemical [inference]

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization

protein localization to organelle [inference]

protein localization to endosome [inference]

protein localization to early endosome

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization

protein localization to organelle [inference]

protein localization to endosome [inference]

protein localization to early endosome

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of protein catabolic process in the vacuole [inference]

negative regulation of lysosomal protein catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of protein catabolic process in the vacuole [inference]

negative regulation of lysosomal protein catabolic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of protein catabolic process in the vacuole [inference]

negative regulation of lysosomal protein catabolic process

regulation of catabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of protein catabolic process in the vacuole [inference]

negative regulation of lysosomal protein catabolic process

regulation of protein catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of protein catabolic process in the vacuole [inference]

negative regulation of lysosomal protein catabolic process

regulation of protein catabolic process in the vacuole [inference]

negative regulation of protein catabolic process in the vacuole [inference]

negative regulation of lysosomal protein catabolic process

regulation of lysosomal protein catabolic process [inference]

negative regulation of lysosomal protein catabolic process

regulation of nitrogen compound metabolic process [inference]

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of protein catabolic process in the vacuole [inference]

negative regulation of lysosomal protein catabolic process

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of protein catabolic process in the vacuole [inference]

negative regulation of lysosomal protein catabolic process

regulation of protein catabolic process in the vacuole [inference]

negative regulation of protein catabolic process in the vacuole [inference]

negative regulation of lysosomal protein catabolic process

regulation of lysosomal protein catabolic process [inference]

negative regulation of lysosomal protein catabolic process

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of protein catabolic process in the vacuole [inference]

negative regulation of lysosomal protein catabolic process

regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of protein catabolic process in the vacuole [inference]

negative regulation of lysosomal protein catabolic process

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of protein catabolic process in the vacuole [inference]

negative regulation of lysosomal protein catabolic process

regulation of protein catabolic process in the vacuole [inference]

negative regulation of protein catabolic process in the vacuole [inference]

negative regulation of lysosomal protein catabolic process

regulation of lysosomal protein catabolic process [inference]

negative regulation of lysosomal protein catabolic process

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of protein catabolic process in the vacuole [inference]

negative regulation of lysosomal protein catabolic process

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of protein catabolic process in the vacuole [inference]

negative regulation of lysosomal protein catabolic process

regulation of protein catabolic process in the vacuole [inference]

negative regulation of protein catabolic process in the vacuole [inference]

negative regulation of lysosomal protein catabolic process

regulation of lysosomal protein catabolic process [inference]

negative regulation of lysosomal protein catabolic process

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of protein catabolic process in the vacuole [inference]

negative regulation of lysosomal protein catabolic process

regulation of localization [inference]

regulation of cellular localization [inference]

regulation of protein localization [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to endosome [inference]

positive regulation of protein localization to early endosome

regulation of protein localization to endosome [inference]

regulation of protein localization to early endosome [inference]

positive regulation of protein localization to early endosome

positive regulation of protein localization to endosome [inference]

positive regulation of protein localization to early endosome

regulation of locomotion [inference]

regulation of cell motility [inference]

regulation of cell migration

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to endosome [inference]

positive regulation of protein localization to early endosome

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of protein catabolic process in the vacuole [inference]

negative regulation of lysosomal protein catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of protein catabolic process in the vacuole [inference]

negative regulation of lysosomal protein catabolic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of protein catabolic process in the vacuole [inference]

negative regulation of lysosomal protein catabolic process

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to endosome [inference]

positive regulation of protein localization to early endosome

regulation of cellular localization [inference]

regulation of protein localization [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to endosome [inference]

positive regulation of protein localization to early endosome

regulation of protein localization to endosome [inference]

regulation of protein localization to early endosome [inference]

positive regulation of protein localization to early endosome

positive regulation of protein localization to endosome [inference]

positive regulation of protein localization to early endosome

regulation of cell motility [inference]

regulation of cell migration

Displaying **all 3** entries
GO Term	Evidence Code	PMID
membrane
lysosome	IEA
Golgi membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

Displaying **all 2** entries
GO Term	Evidence Code	PMID
glycosyltransferase activity	IBA IDA	24619415
beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	IMP ISO ISS	25592972 26467158

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity

catalytic activity, acting on a protein [inference]

catalytic activity, acting on a glycoprotein [inference]

beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase

Functional Category

M: Cell wall/membrane/envelope biogenesis
P: Inorganic ion transport and metabolism
V: Defense mechanisms

Displaying **all 3** entries
Gene Ontology
N-acetylglucosamine metabolic process
beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity
protein N-linked glycosylation

Displaying 1 entry
InterPro
Glycosyl transferase, family 17

KEGG BRITE Database

Orthology

K00737

Name

beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase [EC:2.4.1.144]

References

9061364

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R05986	2.4.1.144	G39213VZ	G59471TH

Ortholog

Displaying entries **1 - 10** of **115** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	4248		HGNC:7046	HUMAN60658
Rattus norvegicus	29582	10116_1:002a22	RGD:3084	RATNO38097
Drosophila melanogaster	318981		FB:FBgn0051849
Pan troglodytes	470218			PANTR26632
Bos taurus	520087			BOVIN30699
Danio rerio	553676		ZFIN:ZDB-GENE-050522-249
Danio rerio	570828		ZFIN:ZDB-GENE-130820-2	DANRE39390
Macaca mulatta	703643			MACMU00570
Monodelphis domestica	100012345			MONDO34995
Ornithorhynchus anatinus	100090777			ORNAN05616

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Summary

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Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements