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Repository for lectin-assisted multimodality data

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Guidelines

MIRAGE

Ground-like domain-containing protein

Summary

Gene Symbol

grd-2

Organism

Caenorhabditis elegans

External Links

NCBI Gene

180349

PubChem

180349

Alliance of Genome Resources

WB:WBGene00001691

Annotation

Keyword

Developmental protein
Reference proteome
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9XV14

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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2

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GO Term	Evidence Code	PMID
cell-cell signaling	IEA
multicellular organism development	IEA
intein-mediated protein splicing
protein autoprocessing	IEA
system development	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing [inference]

protein autoprocessing

protein splicing [inference]

intein-mediated protein splicing

protein maturation [inference]

protein processing [inference]

protein autoprocessing

protein splicing [inference]

intein-mediated protein splicing

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing [inference]

protein autoprocessing

protein splicing [inference]

intein-mediated protein splicing

protein maturation [inference]

protein processing [inference]

protein autoprocessing

protein splicing [inference]

intein-mediated protein splicing

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing [inference]

protein autoprocessing

protein splicing [inference]

intein-mediated protein splicing

protein maturation [inference]

protein processing [inference]

protein autoprocessing

protein splicing [inference]

intein-mediated protein splicing

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing [inference]

protein autoprocessing

protein splicing [inference]

intein-mediated protein splicing

protein maturation [inference]

protein processing [inference]

protein autoprocessing

protein splicing [inference]

intein-mediated protein splicing

cellular process [inference]

cell communication [inference]

cell-cell signaling

reproductive process [inference]

developmental process involved in reproduction [inference]

genitalia morphogenesis [inference]

male genitalia morphogenesis [inference]

nematode male tail mating organ morphogenesis

male anatomical structure morphogenesis [inference]

male genitalia morphogenesis [inference]

nematode male tail mating organ morphogenesis

multicellular organismal process [inference]

multicellular organism development

developmental process [inference]

developmental process involved in reproduction [inference]

genitalia morphogenesis [inference]

male genitalia morphogenesis [inference]

nematode male tail mating organ morphogenesis

male anatomical structure morphogenesis [inference]

male genitalia morphogenesis [inference]

nematode male tail mating organ morphogenesis

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

genitalia morphogenesis [inference]

male genitalia morphogenesis [inference]

nematode male tail mating organ morphogenesis

sensory organ morphogenesis [inference]

nematode male tail mating organ morphogenesis

male anatomical structure morphogenesis [inference]

male genitalia morphogenesis [inference]

nematode male tail mating organ morphogenesis

anatomical structure development [inference]

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling

Displaying **all 3** entries
GO Term	Evidence Code	PMID
extracellular region	ISS	10523520
extracellular region	IEA
extracellular matrix	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

external encapsulating structure [inference]

extracellular matrix

Displaying **all 3** entries
GO Term	Evidence Code	PMID
endopeptidase activity	ISS	10523520
signaling receptor binding	ISS	10523520
cholesterol binding	ISS	10523520

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity

binding [inference]

protein binding [inference]

signaling receptor binding

lipid binding [inference]

steroid binding [inference]

sterol binding [inference]

cholesterol binding

small molecule binding [inference]

alcohol binding [inference]

cholesterol binding

organic cyclic compound binding [inference]

steroid binding [inference]

sterol binding [inference]

cholesterol binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

hedgehog

Functional Category

L: Replication, recombination and repair
T: Signal transduction mechanisms
X: Mobilome: prophages, transposons

Displaying entries **1 - 10** of 12 in total

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Gene Ontology
calcium ion binding
cell fate specification
cell-cell signaling
hydrolase activity
intein-mediated protein splicing
metal ion binding
patched binding
protein autoprocessing
proteolysis
regulation of gene expression

Displaying **all 8** entries
InterPro
Hedgehog protein, Hint domain
Hedgehog protein
Hedgehog signalling/DD-peptidase zinc-binding domain superfamily
Hedgehog, N-terminal signalling domain
Hint domain C-terminal
Hint domain N-terminal
Hint domain superfamily
Intein N-terminal splicing region

Ortholog

Displaying **all 8** entries
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	3549	Xenbase:XB-GENE-484187
Homo sapiens	6469	HGNC:10848
Xenopus tropicalis	16147	Xenbase:XB-GENE-484187
Homo sapiens	20423	HGNC:10848
Homo sapiens	29499	HGNC:10848
Xenopus tropicalis	180349	Xenbase:XB-GENE-484187
Danio rerio	180638	ZFIN:ZDB-GENE-980526-135
Danio rerio	181300	ZFIN:ZDB-GENE-980526-135

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.4.0

Last updated: December 8, 2025