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Dopamine receptor 1

Summary

Gene Symbol

dop-1

Organism

Caenorhabditis elegans

External Links

NCBI Gene

180714

PubChem

180714

Alliance of Genome Resources

WB:WBGene00001052

Annotation

Keyword

Cell membrane
G-protein coupled receptor
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q86ME5
Q86ME4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
synaptic transmission, dopaminergic	IEA
G protein-coupled receptor signaling pathway	IEA
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	IBA
adenylate cyclase-modulating G protein-coupled receptor signaling pathway	IBA
adenylate cyclase-activating dopamine receptor signaling pathway	IDA	14739932

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

synaptic transmission, dopaminergic

signal transduction [inference]

G protein-coupled receptor signaling pathway

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating dopamine receptor signaling pathway

G protein-coupled serotonin receptor signaling pathway

dopamine receptor signaling pathway

adenylate cyclase-activating dopamine receptor signaling pathway

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

learning [inference]

nonassociative learning [inference]

habituation

behavior [inference]

learning or memory [inference]

learning [inference]

nonassociative learning [inference]

habituation

mechanosensory behavior

response to stimulus [inference]

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

response to food

response to chemical [inference]

response to food

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

synaptic transmission, dopaminergic

regulation of locomotion

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating dopamine receptor signaling pathway

G protein-coupled serotonin receptor signaling pathway

dopamine receptor signaling pathway

adenylate cyclase-activating dopamine receptor signaling pathway

Displaying **all 5** entries
GO Term	Evidence Code	PMID
plasma membrane	IBA
plasma membrane	IEA
membrane	IEA
dendrite	IBA
synapse	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

cell junction [inference]

synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
dopamine neurotransmitter receptor activity, coupled via Gs	IDA	14739932
G protein-coupled receptor activity	IEA
G protein-coupled serotonin receptor activity	IBA
neurotransmitter receptor activity	IBA
signaling receptor activity	IEA

GO Hierarchy

molecular function

binding [inference]

ion binding [inference]

cation binding [inference]

norepinephrine binding

organic cyclic compound binding [inference]

catecholamine binding [inference]

molecular transducer activity [inference]

signaling receptor activity

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

G protein-coupled amine receptor activity [inference]

G protein-coupled serotonin receptor activity

neurotransmitter receptor activity

postsynaptic neurotransmitter receptor activity [inference]

dopamine neurotransmitter receptor activity [inference]

dopamine neurotransmitter receptor activity, coupled via Gs

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

5-hydroxytryptamine receptor

Functional Category

O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
adenylate cyclase-activating adrenergic receptor signaling pathway

Displaying **all 2** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
neuron projection	PMID:14568548
cell projection	PMID:14568548
plasma membrane	PMID:14568548

Ortholog

Displaying **all 10** entries
Species	Gene ID	Alliance of Genome Resources
Xenopus tropicalis	1812	Xenbase:XB-GENE-6035431
Danio rerio	1816	ZFIN:ZDB-GENE-121214-145
Xenopus tropicalis	13488	Xenbase:XB-GENE-6035431
Homo sapiens	13492	HGNC:3026
Homo sapiens	25195	HGNC:3026
Xenopus tropicalis	41726	Xenbase:XB-GENE-6035431
Xenopus tropicalis	42652	Xenbase:XB-GENE-5919679
Xenopus tropicalis	180714	Xenbase:XB-GENE-6035431
Homo sapiens	108705891	HGNC:3026
Xenopus tropicalis	108710578	Xenbase:XB-GENE-6035431

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements