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Guidelines

MIRAGE

Hypoxia up-regulated protein 1

Summary

Gene Symbol

T14G8.3

Organism

Caenorhabditis elegans

External Links

NCBI Gene

181422

PubChem

181422

Alliance of Genome Resources

WB:WBGene00011771

Annotation

Keyword

ATP-binding
Proteomics identification
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q22515

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein folding	IEA
response to stress	IEA
endoplasmic reticulum unfolded protein response	HEP	12186849
IRE1-mediated unfolded protein response	HEP	12186849

GO Hierarchy

biological process

cellular process [inference]

protein folding

signal transduction [inference]

endoplasmic reticulum unfolded protein response

IRE1-mediated unfolded protein response

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

endoplasmic reticulum unfolded protein response

IRE1-mediated unfolded protein response

response to stimulus [inference]

response to stress

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

endoplasmic reticulum unfolded protein response

IRE1-mediated unfolded protein response

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

endoplasmic reticulum unfolded protein response

IRE1-mediated unfolded protein response

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

endoplasmic reticulum unfolded protein response

IRE1-mediated unfolded protein response

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum chaperone complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

endoplasmic reticulum protein-containing complex [inference]

endoplasmic reticulum chaperone complex

Displaying **all 3** entries
GO Term	Evidence Code	PMID
adenyl-nucleotide exchange factor activity	IBA
ATP binding	IEA
ATP-dependent protein folding chaperone	IEA

GO Hierarchy

molecular function

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl-nucleotide exchange factor activity

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl-nucleotide exchange factor activity

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

protein folding chaperone [inference]

ATP-dependent protein folding chaperone

molecular function regulator activity [inference]

ATPase regulator activity [inference]

adenyl-nucleotide exchange factor activity

ATP-dependent activity [inference]

ATP-dependent protein folding chaperone

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

protein heat shock protein

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
ATP binding
ATP-dependent protein folding chaperone
endoplasmic reticulum unfolded protein response
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway
nucleotide binding

Displaying **all 4** entries
InterPro
ATPase, nucleotide binding domain
Heat shock protein 70 family
Heat shock protein 70kD, C-terminal domain superfamily
Heat shock protein 70kD, peptide-binding domain superfamily

Ortholog

Displaying **all 6** entries
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	10525	Xenbase:XB-GENE-921821
Xenopus tropicalis	12282	Xenbase:XB-GENE-921821
Xenopus tropicalis	174033	Xenbase:XB-GENE-921821
Xenopus tropicalis	181422	Xenbase:XB-GENE-921821
Xenopus tropicalis	192235	Xenbase:XB-GENE-921821
Xenopus tropicalis	853789	Xenbase:XB-GENE-921821

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.4.0

Last updated: December 8, 2025