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Guidelines

MIRAGE

tyrosine hydroxylase

Summary

Gene Symbol

Th

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

21823

PubChem

21823

Alliance of Genome Resources

MGI:98735

Annotation

Keyword

Catecholamine biosynthesis
Cell projection
Cytoplasm
Cytoplasmic vesicle
Direct protein sequencing
Iron
Metal-binding
Monooxygenase
Neurotransmitter biosynthesis
Nucleus
Phosphoprotein
Reference proteome
Synapse

Proteins

Displaying 1 entry
UniProt	Protein Name
P24529	Tyrosine 3-hydroxylase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 68 in total

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GO Term	Evidence Code	PMID
response to hypoxia	ISO
response to hypoxia	IBA
response to hypoxia	IEA
synaptic transmission, dopaminergic	IMP	12604788 15317940
response to amphetamine	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amine biosynthetic process [inference]

biogenic amine biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

aromatic amino acid metabolic process [inference]

tyrosine metabolic process [inference]

dopamine biosynthetic process from tyrosine

alpha-amino acid metabolic process [inference]

tyrosine metabolic process [inference]

dopamine biosynthetic process from tyrosine

sphingolipid metabolic process

amine metabolic process [inference]

biogenic amine metabolic process [inference]

catecholamine metabolic process [inference]

epinephrine metabolic process [inference]

epinephrine biosynthetic process

norepinephrine metabolic process [inference]

norepinephrine biosynthetic process

dopamine metabolic process [inference]

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

biogenic amine biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

amine biosynthetic process [inference]

biogenic amine biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

alkaloid metabolic process [inference]

isoquinoline alkaloid metabolic process

organonitrogen compound biosynthetic process [inference]

amine biosynthetic process [inference]

biogenic amine biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

biosynthetic process [inference]

cellular biosynthetic process [inference]

aromatic compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

catechol-containing compound biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

cellular nitrogen compound biosynthetic process [inference]

amine biosynthetic process [inference]

biogenic amine biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

organic substance biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

catechol-containing compound biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

organonitrogen compound biosynthetic process [inference]

amine biosynthetic process [inference]

biogenic amine biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

organic hydroxy compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

catechol-containing compound biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

secondary metabolic process [inference]

toxin metabolic process [inference]

phytoalexin metabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

aromatic amino acid metabolic process [inference]

tyrosine metabolic process [inference]

dopamine biosynthetic process from tyrosine

alpha-amino acid metabolic process [inference]

tyrosine metabolic process [inference]

dopamine biosynthetic process from tyrosine

phthalate metabolic process

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

cellular aromatic compound metabolic process [inference]

aromatic amino acid metabolic process [inference]

tyrosine metabolic process [inference]

dopamine biosynthetic process from tyrosine

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

epinephrine metabolic process [inference]

epinephrine biosynthetic process

norepinephrine metabolic process [inference]

norepinephrine biosynthetic process

dopamine metabolic process [inference]

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

catechol-containing compound biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

phenol-containing compound biosynthetic process [inference]

catechol-containing compound biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

aromatic compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

catechol-containing compound biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

benzene-containing compound metabolic process [inference]

phthalate metabolic process

toxin metabolic process [inference]

phytoalexin metabolic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amine biosynthetic process [inference]

biogenic amine biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

cellular biosynthetic process [inference]

aromatic compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

catechol-containing compound biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

cellular nitrogen compound biosynthetic process [inference]

amine biosynthetic process [inference]

biogenic amine biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

cellular lipid metabolic process [inference]

fatty acid metabolic process

membrane lipid metabolic process [inference]

sphingolipid metabolic process

isoprenoid metabolic process [inference]

terpene metabolic process

primary metabolic process [inference]

amino acid metabolic process [inference]

aromatic amino acid metabolic process [inference]

tyrosine metabolic process [inference]

dopamine biosynthetic process from tyrosine

alpha-amino acid metabolic process [inference]

tyrosine metabolic process [inference]

dopamine biosynthetic process from tyrosine

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process

membrane lipid metabolic process [inference]

sphingolipid metabolic process

isoprenoid metabolic process [inference]

terpene metabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

aromatic amino acid metabolic process [inference]

tyrosine metabolic process [inference]

dopamine biosynthetic process from tyrosine

alpha-amino acid metabolic process [inference]

tyrosine metabolic process [inference]

dopamine biosynthetic process from tyrosine

phthalate metabolic process

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

aromatic amino acid metabolic process [inference]

tyrosine metabolic process [inference]

dopamine biosynthetic process from tyrosine

alpha-amino acid metabolic process [inference]

tyrosine metabolic process [inference]

dopamine biosynthetic process from tyrosine

phthalate metabolic process

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process

membrane lipid metabolic process [inference]

sphingolipid metabolic process

isoprenoid metabolic process [inference]

terpene metabolic process

hydrocarbon metabolic process [inference]

terpene metabolic process

carbohydrate derivative metabolic process [inference]

glycosyl compound metabolic process [inference]

glycoside metabolic process

organic cyclic compound metabolic process [inference]

aromatic amino acid metabolic process [inference]

tyrosine metabolic process [inference]

dopamine biosynthetic process from tyrosine

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

epinephrine metabolic process [inference]

epinephrine biosynthetic process

norepinephrine metabolic process [inference]

norepinephrine biosynthetic process

dopamine metabolic process [inference]

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

catechol-containing compound biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

phenol-containing compound biosynthetic process [inference]

catechol-containing compound biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

benzene-containing compound metabolic process [inference]

phthalate metabolic process

organic cyclic compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

catechol-containing compound biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

aromatic amino acid metabolic process [inference]

tyrosine metabolic process [inference]

dopamine biosynthetic process from tyrosine

alpha-amino acid metabolic process [inference]

tyrosine metabolic process [inference]

dopamine biosynthetic process from tyrosine

sphingolipid metabolic process

amine metabolic process [inference]

biogenic amine metabolic process [inference]

catecholamine metabolic process [inference]

epinephrine metabolic process [inference]

epinephrine biosynthetic process

norepinephrine metabolic process [inference]

norepinephrine biosynthetic process

dopamine metabolic process [inference]

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

biogenic amine biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

amine biosynthetic process [inference]

biogenic amine biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

alkaloid metabolic process [inference]

isoquinoline alkaloid metabolic process

organonitrogen compound biosynthetic process [inference]

amine biosynthetic process [inference]

biogenic amine biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

organic substance biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

catechol-containing compound biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

organonitrogen compound biosynthetic process [inference]

amine biosynthetic process [inference]

biogenic amine biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

organic hydroxy compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

catechol-containing compound biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

organic hydroxy compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

epinephrine metabolic process [inference]

epinephrine biosynthetic process

norepinephrine metabolic process [inference]

norepinephrine biosynthetic process

dopamine metabolic process [inference]

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

catechol-containing compound biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

phenol-containing compound biosynthetic process [inference]

catechol-containing compound biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

organic hydroxy compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

catechol-containing compound biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, dopaminergic

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

aromatic amino acid metabolic process [inference]

tyrosine metabolic process [inference]

dopamine biosynthetic process from tyrosine

alpha-amino acid metabolic process [inference]

tyrosine metabolic process [inference]

dopamine biosynthetic process from tyrosine

phthalate metabolic process

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

cellular aromatic compound metabolic process [inference]

aromatic amino acid metabolic process [inference]

tyrosine metabolic process [inference]

dopamine biosynthetic process from tyrosine

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

epinephrine metabolic process [inference]

epinephrine biosynthetic process

norepinephrine metabolic process [inference]

norepinephrine biosynthetic process

dopamine metabolic process [inference]

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

catechol-containing compound biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

phenol-containing compound biosynthetic process [inference]

catechol-containing compound biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

aromatic compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

catechol-containing compound biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

benzene-containing compound metabolic process [inference]

phthalate metabolic process

toxin metabolic process [inference]

phytoalexin metabolic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amine biosynthetic process [inference]

biogenic amine biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

cellular biosynthetic process [inference]

aromatic compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

catechol-containing compound biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

cellular nitrogen compound biosynthetic process [inference]

amine biosynthetic process [inference]

biogenic amine biosynthetic process [inference]

catecholamine biosynthetic process

dopamine biosynthetic process

dopamine biosynthetic process from tyrosine

cellular lipid metabolic process [inference]

fatty acid metabolic process

membrane lipid metabolic process [inference]

sphingolipid metabolic process

isoprenoid metabolic process [inference]

terpene metabolic process

cellular developmental process [inference]

cell development [inference]

neuron development [inference]

photoreceptor cell development [inference]

eye photoreceptor cell development

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to manganese ion

cellular response to organic substance [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

cellular response to organonitrogen compound [inference]

cellular response to alkaloid

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to alkaloid

cellular response to oxygen-containing compound [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

reproductive process [inference]

reproductive behavior [inference]

mating behavior

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of light stimulus [inference]

visual perception

cognition [inference]

learning or memory [inference]

behavior [inference]

learning or memory [inference]

rhythmic behavior [inference]

circadian behavior [inference]

circadian sleep/wake cycle

locomotory behavior

feeding behavior [inference]

eating behavior

reproductive behavior [inference]

mating behavior

social behavior

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis

embryonic organ morphogenesis [inference]

embryonic eye morphogenesis [inference]

embryonic camera-type eye morphogenesis

sensory organ morphogenesis [inference]

eye morphogenesis [inference]

embryonic eye morphogenesis [inference]

embryonic camera-type eye morphogenesis

embryonic morphogenesis [inference]

embryonic organ morphogenesis [inference]

embryonic eye morphogenesis [inference]

embryonic camera-type eye morphogenesis

anatomical structure development [inference]

cerebral cortex development

cell development [inference]

neuron development [inference]

photoreceptor cell development [inference]

eye photoreceptor cell development

animal organ development [inference]

heart development

cellular developmental process [inference]

cell development [inference]

neuron development [inference]

photoreceptor cell development [inference]

eye photoreceptor cell development

anatomical structure regression [inference]

hyaloid vascular plexus regression

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular glucose homeostasis [inference]

cellular response to glucose stimulus

chemical homeostasis [inference]

carbohydrate homeostasis [inference]

glucose homeostasis [inference]

intracellular glucose homeostasis [inference]

cellular response to glucose stimulus

intracellular chemical homeostasis [inference]

intracellular glucose homeostasis [inference]

cellular response to glucose stimulus

rhythmic process [inference]

circadian rhythm [inference]

circadian behavior [inference]

circadian sleep/wake cycle

response to stimulus [inference]

response to stress [inference]

response to hypoxia

response to osmotic stress [inference]

response to salt stress

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to abiotic stimulus [inference]

response to osmotic stress [inference]

response to salt stress

response to radiation [inference]

response to light stimulus

response to electrical stimulus

response to oxygen levels [inference]

response to decreased oxygen levels [inference]

response to hypoxia

response to endogenous stimulus [inference]

response to hormone [inference]

response to peptide hormone

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

response to corticosterone

response to mineralocorticoid [inference]

response to corticosterone

response to growth factor [inference]

cellular response to growth factor stimulus

cellular response to endogenous stimulus [inference]

cellular response to growth factor stimulus

cellular response to organonitrogen compound [inference]

cellular response to alkaloid

response to activity

response to chemical [inference]

response to xenobiotic stimulus [inference]

cellular response to xenobiotic stimulus

response to toxic substance [inference]

response to herbicide

response to insecticide [inference]

response to pyrethroid

response to organic substance [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to hormone [inference]

response to peptide hormone

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

response to corticosterone

response to mineralocorticoid [inference]

response to corticosterone

response to carbohydrate [inference]

response to monosaccharide [inference]

response to hexose [inference]

response to glucose [inference]

cellular response to glucose stimulus

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

cellular response to carbohydrate stimulus [inference]

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

response to organonitrogen compound [inference]

response to amine [inference]

response to amphetamine

response to alkaloid [inference]

cellular response to alkaloid

cellular response to organonitrogen compound [inference]

cellular response to alkaloid

response to peptide [inference]

response to peptide hormone

response to organic cyclic compound [inference]

response to estradiol

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

response to corticosterone

response to mineralocorticoid [inference]

response to corticosterone

response to lipid [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

response to corticosterone

response to mineralocorticoid [inference]

response to corticosterone

response to ether

cellular response to organic substance [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

cellular response to organonitrogen compound [inference]

cellular response to alkaloid

response to alcohol [inference]

response to ketone [inference]

response to corticosterone

response to inorganic substance [inference]

response to metal ion [inference]

response to manganese ion [inference]

cellular response to manganese ion

response to zinc ion

cellular response to metal ion [inference]

cellular response to manganese ion

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to manganese ion

response to nicotine [inference]

cellular response to nicotine

cellular response to chemical stimulus [inference]

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to manganese ion

cellular response to organic substance [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

cellular response to organonitrogen compound [inference]

cellular response to alkaloid

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to alkaloid

cellular response to oxygen-containing compound [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to amine [inference]

response to amphetamine

response to alkaloid [inference]

cellular response to alkaloid

cellular response to organonitrogen compound [inference]

cellular response to alkaloid

response to peptide [inference]

response to peptide hormone

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to alkaloid

response to oxygen-containing compound [inference]

response to carbohydrate [inference]

response to monosaccharide [inference]

response to hexose [inference]

response to glucose [inference]

cellular response to glucose stimulus

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

cellular response to carbohydrate stimulus [inference]

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

response to alcohol [inference]

response to peptide [inference]

response to peptide hormone

response to ketone [inference]

response to corticosterone

cellular response to oxygen-containing compound [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to manganese ion

cellular response to organic substance [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

cellular response to organonitrogen compound [inference]

cellular response to alkaloid

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to alkaloid

cellular response to oxygen-containing compound [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

localization [inference]

establishment of localization [inference]

transport [inference]

neurotransmitter transport [inference]

neurotransmitter loading into synaptic vesicle [inference]

aminergic neurotransmitter loading into synaptic vesicle

organic substance transport [inference]

amine transport [inference]

aminergic neurotransmitter loading into synaptic vesicle

nitrogen compound transport [inference]

amine transport [inference]

aminergic neurotransmitter loading into synaptic vesicle

establishment of localization in cell [inference]

neurotransmitter loading into synaptic vesicle [inference]

aminergic neurotransmitter loading into synaptic vesicle

biological process involved in intraspecies interaction between organisms [inference]

social behavior

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, dopaminergic

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of blood circulation [inference]

regulation of heart contraction

Displaying entries **1 - 5** of 31 in total

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GO Term	Evidence Code	PMID
nucleus	ISO
nucleus	IDA	15643613
cytoplasm	ISO
cytoplasm	IDA	10707987
cytoplasm	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane

pigment granule membrane [inference]

melanosome membrane

bounding membrane of organelle [inference]

pigment granule membrane [inference]

melanosome membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

perikaryon

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum [inference]

smooth endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum [inference]

smooth endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

cell body [inference]

neuronal cell body

perinuclear region of cytoplasm

side of membrane [inference]

cytoplasmic side of membrane [inference]

cytoplasmic side of plasma membrane

presynapse [inference]

terminal bouton

Displaying entries **1 - 5** of 22 in total

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GO Term	Evidence Code	PMID
monooxygenase activity	ISO
tyrosine 3-monooxygenase activity	ISO
tyrosine 3-monooxygenase activity	TAS	7592982
tyrosine 3-monooxygenase activity	IBA
ferrous iron binding	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

monooxygenase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen [inference]

tyrosine 3-monooxygenase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen [inference]

tyrosine 3-monooxygenase activity

binding [inference]

protein binding [inference]

small molecule binding

oxygen binding

organic acid binding [inference]

carboxylic acid binding [inference]

amino acid binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

amino acid binding

cation binding [inference]

dopamine binding

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding [inference]

organic cyclic compound binding [inference]

tetrahydrobiopterin binding

catecholamine binding [inference]

dopamine binding

sulfur compound binding [inference]

ferric iron binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

tryptophan 5-hydroxylase

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
aromatic amino acid metabolic process
iron ion binding
metal ion binding
monooxygenase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
oxidoreductase activity

Displaying **all 8** entries
InterPro
ACT domain
ACT-like domain
Aromatic amino acid hydroxylase superfamily
Aromatic amino acid hydroxylase, C-terminal
Aromatic amino acid hydroxylase, iron/copper binding site
Aromatic amino acid hydroxylase
Aromatic amino acid monoxygenase, C-terminal domain superfamily
Tyrosine 3-monooxygenase-like

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026