Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
fatty acid synthase
Summary
- Gene Symbol
-
- FASN
- Aliases
-
- 3-hydroxyacyl-[acyl-carrier-protein] dehydratase
- 3-oxoacyl-[acyl-carrier-protein] reductase
- 3-oxoacyl-[acyl-carrier-protein] synthase
- Acyl-[acyl-carrier-protein] hydrolase
- Enoyl-[acyl-carrier-protein] reductase
- FAS
- SDR27X1
- [Acyl-carrier-protein] S-acetyltransferase
- [Acyl-carrier-protein] S-malonyltransferase
- short chain dehydrogenase/reductase family 27X, member 1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Cytoplasm
- Direct protein sequencing
- Fatty acid biosynthesis
- Hydrolase
- Isopeptide bond
- Lyase
- Multifunctional enzyme
- NAD
- NADP
- Oxidoreductase
- Phosphopantetheine
- Phosphoprotein
- Pyridoxal phosphate
- Reference proteome
- S-nitrosylation
- Transferase
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| P49327 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| neutrophil differentiation | ||
| glandular epithelial cell development |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| glycogen granule | ||
| melanosome | ||
| cytosol | ||
| cytoplasm | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| [acyl-carrier-protein] S-acetyltransferase activity | ||
| [acyl-carrier-protein] S-malonyltransferase activity | ||
| fatty acid synthase activity | ||
| (3R)-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity | ||
| phosphopantetheine binding |
GO Hierarchy
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:11476 | osteoporosis | |
| DOID:11634 | myxedema | |
| DOID:1168 | familial hyperlipidemia | |
| DOID:11714 | gestational diabetes | |
| DOID:11722 | myotonic dystrophy type 1 | |
| DOID:11836 | clubfoot | |
| DOID:11870 | Pick's disease | |
| DOID:11934 | head and neck cancer | |
| DOID:11984 | hypertrophic cardiomyopathy | |
| DOID:12123 | postinflammatory pulmonary fibrosis |
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP002507
- Gene Name
- fatty acid synthase
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 112920917 | VULVU13634 | ||
| 123777917 | URSAM23045 | ||
| 100468470 | AILME19094 | ||
| 101693535 | MUSPF14866 | ||
| 100270775 | FELCA31132 | ||
| 122206187 | PANLE04598 | ||
| 100674176 | LOXAF07100 | ||
| 397561 | PIGXX01624 | ||
| 281152 | BOVIN13729 | ||
| 100861286 | CAPHI11201 |
