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Guidelines
MIRAGE
vascular endothelial growth factor A
Summary
- Gene Symbol
-
- Vegfa
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Alternative initiation
- Alternative promoter usage
- Alternative splicing
- Angiogenesis
- Cell membrane
- Cytoplasm
- Developmental protein
- Differentiation
- Disulfide bond
- Endoplasmic reticulum
- Extracellular matrix
- Glycoprotein
- Golgi apparatus
- Growth factor
- Heparin-binding
- Mitogen
- Nucleus
- Reference proteome
- Proteins
| UniProt | Protein Name |
|---|---|
| Q00731 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of sprouting angiogenesis | ||
| positive regulation of sprouting angiogenesis | ||
| positive regulation of epithelial tube formation | ||
| negative regulation of blood-brain barrier permeability | ||
| negative regulation of blood-brain barrier permeability |
GO Hierarchy
- regulation of nitric oxide mediated signal transduction
- positive regulation of cell division
- regulation of nitric oxide mediated signal transduction
- regulation of nitric oxide mediated signal transduction
- positive regulation of cell division
biological process
metabolic process [inference]
cellular process [inference]
signal transduction
multicellular organismal process [inference]
developmental process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of nitrogen compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
negative regulation of macromolecule metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of RNA metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
regulation of signal transduction [inference]
positive regulation of signal transduction
regulation of intracellular signal transduction [inference]
regulation of MAPK cascade [inference]
positive regulation of intracellular signal transduction [inference]
positive regulation of signaling [inference]
positive regulation of signal transduction
regulation of localization [inference]
regulation of growth
regulation of locomotion [inference]
positive regulation of locomotion [inference]
regulation of cell motility [inference]
regulation of cell migration [inference]
positive regulation of cell motility [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of signaling [inference]
positive regulation of signal transduction
positive regulation of locomotion [inference]
positive regulation of cellular process [inference]
positive regulation of cell population proliferation
positive regulation of cell communication [inference]
positive regulation of signal transduction
positive regulation of cellular metabolic process [inference]
positive regulation of cell motility [inference]
positive regulation of response to stimulus [inference]
positive regulation of signal transduction
positive regulation of developmental process [inference]
positive regulation of multicellular organismal process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of signal transduction [inference]
positive regulation of signal transduction
regulation of intracellular signal transduction [inference]
regulation of MAPK cascade [inference]
positive regulation of intracellular signal transduction [inference]
regulation of response to external stimulus [inference]
positive regulation of response to stimulus [inference]
positive regulation of signal transduction
regulation of developmental process [inference]
regulation of anatomical structure morphogenesis [inference]
regulation of cell differentiation [inference]
positive regulation of developmental process [inference]
regulation of multicellular organismal development [inference]
regulation of cellular process [inference]
signal transduction
regulation of cell communication [inference]
regulation of signal transduction [inference]
positive regulation of signal transduction
regulation of intracellular signal transduction [inference]
regulation of MAPK cascade [inference]
positive regulation of intracellular signal transduction [inference]
positive regulation of cell communication [inference]
positive regulation of signal transduction
regulation of cell adhesion [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of cell population proliferation [inference]
positive regulation of cell population proliferation
regulation of programmed cell death [inference]
regulation of cellular component biogenesis [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
positive regulation of cell population proliferation
positive regulation of cell communication [inference]
positive regulation of signal transduction
positive regulation of cellular metabolic process [inference]
positive regulation of cell motility [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of cell motility [inference]
regulation of cell migration [inference]
positive regulation of cell motility [inference]
regulation of multicellular organismal process [inference]
regulation of epithelial cell migration [inference]
positive regulation of multicellular organismal process [inference]
regulation of multicellular organismal development [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region |
|
|
| basement membrane | ||
| extracellular space | ||
| extracellular space | ||
| extracellular space |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| fibronectin binding | ||
| fibronectin binding | ||
| signaling receptor binding |
|
|
| cytokine activity | ||
| cytokine activity |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Vascular endothelial growth factor
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| growth factor activity |
| InterPro |
|---|
| Cystine-knot cytokine |
| PDGF/VEGF domain |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060193 | amyotrophic lateral sclerosis type 1 | |
| DOID:11198 | DiGeorge syndrome | |
| DOID:12716 | newborn respiratory distress syndrome | |
| DOID:8893 | psoriasis |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 7422 | Xenbase:XB-GENE-485744 | ||
| 22339 | Xenbase:XB-GENE-485744 | ||
| 30682 | Xenbase:XB-GENE-485744 | ||
| 83785 | Xenbase:XB-GENE-485744 | ||
| 100012132 | MONDO14224 | ||
| 123796996 | URSAM03403 |
