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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
adrenoceptor beta 1
Summary
- Gene Symbol
-
- Adrb1
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Cell membrane
- Disulfide bond
- Endosome
- G-protein coupled receptor
- Glycoprotein
- Palmitate
- Phosphoprotein
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| P18090 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| diet induced thermogenesis |
GO Hierarchy
biological process
metabolic process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of localization [inference]
regulation of growth [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
regulation of biological quality [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| Schaffer collateral - CA1 synapse | ||
| membrane | ||
| early endosome | ||
| postsynapse | ||
| neuronal dense core vesicle |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential | ||
| amine binding | ||
| protein heterodimerization activity | ||
| alpha-2A adrenergic receptor binding |
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- 7TM GPCR, serpentine receptor class v (Srv)
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| InterPro |
|---|
| Adrenoceptor family |
| Beta 1 adrenoceptor |
| G protein-coupled receptor, rhodopsin-like |
| GPCR, rhodopsin-like, 7TM |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050848 | obstructive sleep apnea | |
| DOID:10763 | hypertension | |
| DOID:11664 | nephrosclerosis | |
| DOID:12930 | dilated cardiomyopathy | |
| DOID:13544 | low tension glaucoma | |
| DOID:1485 | cystic fibrosis | |
| DOID:1591 | renovascular hypertension | |
| DOID:1712 | aortic valve stenosis | |
| DOID:3083 | chronic obstructive pulmonary disease | |
| DOID:4195 | hyperglycemia |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 113586622 | ELEEL38049 | |||
| 113834807 | 10029_0:002954 | |||
| 113884527 | BOBOX21301 | |||
| 114088707 | 93162_0:000da9 | |||
| 114627832 | 491861_0:0002b3 | |||
| 114697069 | 10041_0:0007e8 | |||
| 115531030 | GADMO23116 | |||
| 115607979 | STRHB04664 | |||
| 116104027 | 35658_0:002c74 | |||
| 116891330 | 10117_0:000fa6 |
