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aldehyde dehydrogenase 6 family member A1

Summary

Gene Symbol

ALDH6A1

Organism

Bos taurus (cattle)

External Links

NCBI Gene: 327692
KEGG Gene ID: bta:327692
PubChem: 327692

Annotation

Keyword

Acetylation
Direct protein sequencing
Mitochondrion
NAD
Oxidoreductase
Phosphoprotein
Reference proteome
Transit peptide

Proteins

Displaying 1 entry
UniProt	Protein Name
Q07536	Aldehyde dehydrogenase family 6 member A1 Malonate-semialdehyde dehydrogenase [acylating]

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
valine catabolic process	IEA	30032202
thymine catabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

cellular nitrogen compound catabolic process [inference]

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

branched-chain amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

cellular nitrogen compound catabolic process [inference]

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

heterocycle catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

organic cyclic compound catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

branched-chain amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

cellular nitrogen compound catabolic process [inference]

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

cellular nitrogen compound catabolic process [inference]

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

heterocycle catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

heterocycle catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

amino acid metabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

branched-chain amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

branched-chain amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

branched-chain amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

organic cyclic compound catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

branched-chain amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

organic cyclic compound catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

branched-chain amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

cellular nitrogen compound catabolic process [inference]

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

cellular nitrogen compound catabolic process [inference]

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

heterocycle catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

heterocycle catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

Displaying 1 entry
GO Term	Evidence Code	PMID
mitochondrion	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 2** entries
GO Term	Evidence Code	PMID
malonate-semialdehyde dehydrogenase (acetylating) activity	IEA	30032202
methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [inference]

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00140

Name

malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]

References

Rhea

H₂O + CoA + NAD⁺ + 2-methyl-3-oxopropanoate

H⁺ + hydrogencarbonate + propanoyl-CoA + NADH

Enzyme

1.2.1.27

PMID

H₂O + 3-oxopropanoate + CoA + NAD⁺

H⁺ + hydrogencarbonate + acetyl-CoA + NADH

Enzyme

1.2.1.27

PMID

16332250

Ortholog

Displaying entries **31 - 40** of 95 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Macaca fascicularis	102121682		MACFA39627
Macaca mulatta	698755		MACMU42721
Macaca nemestrina	105495810		MACNE43527
Papio anubis	101010014		PAPAN36779
Mandrillus leucophaeus	105540821		MANLE21563
Gorilla gorilla gorilla	101151273		GORGO08984
Pan paniscus	100977732		PANPA12336
Pan troglodytes	467506		PANTR09145
Pongo abelii	100171652		PONAB08492
Homo sapiens	4329		HUMAN20251

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Acknowledgements

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Last updated: August 19, 2024