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FAT atypical cadherin 4

Summary

Gene Symbol

Fat4

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

329628

PubChem

329628

Alliance of Genome Resources

MGI:3045256

Annotation

Keyword

Alternative splicing
Calcium
Cell adhesion
Disulfide bond
EGF-like domain
Glycoprotein
Phosphoprotein
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q2PZL6	FAT tumor suppressor homolog 4 Fat-like cadherin protein FAT-J

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
branching involved in ureteric bud morphogenesis	IMP	21303848
establishment of planar polarity	IC	21303848
kidney development	IMP	21303848
heart morphogenesis	IMP	21303848
plasma membrane organization	IMP	19506035

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

fibroblast growth factor receptor signaling pathway

Notch signaling pathway

intracellular signal transduction [inference]

hippo signaling

cell population proliferation [inference]

mesenchymal cell proliferation [inference]

condensed mesenchymal cell proliferation

cellular developmental process [inference]

cell differentiation [inference]

neurogenesis

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

inner ear receptor cell stereocilium organization

membrane organization [inference]

plasma membrane organization

multicellular organismal process [inference]

ossification [inference]

ossification involved in bone maturation

morphogenesis of a branching structure [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube [inference]

branching involved in ureteric bud morphogenesis

developmental process [inference]

anatomical structure morphogenesis [inference]

morphogenesis of a branching structure [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube [inference]

branching involved in ureteric bud morphogenesis

establishment of tissue polarity [inference]

establishment of planar polarity

animal organ morphogenesis [inference]

heart morphogenesis

tube morphogenesis [inference]

branching morphogenesis of an epithelial tube [inference]

branching involved in ureteric bud morphogenesis

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube [inference]

branching involved in ureteric bud morphogenesis

anatomical structure development [inference]

cerebral cortex development

tube development [inference]

digestive tract development

animal organ development [inference]

kidney development

nephron development

cellular developmental process [inference]

cell differentiation [inference]

neurogenesis

biological regulation [inference]

regulation of biological process [inference]

regulation of developmental process [inference]

regulation of cell differentiation [inference]

regulation of epithelial cell differentiation [inference]

regulation of epithelial cell differentiation involved in kidney development [inference]

regulation of nephron tubule epithelial cell differentiation [inference]

regulation of metanephric nephron tubule epithelial cell differentiation

regulation of multicellular organismal development [inference]

regulation of epithelial cell differentiation [inference]

regulation of epithelial cell differentiation involved in kidney development [inference]

regulation of nephron tubule epithelial cell differentiation [inference]

regulation of metanephric nephron tubule epithelial cell differentiation

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

fibroblast growth factor receptor signaling pathway

Notch signaling pathway

intracellular signal transduction [inference]

hippo signaling

regulation of cell differentiation [inference]

regulation of epithelial cell differentiation [inference]

regulation of epithelial cell differentiation involved in kidney development [inference]

regulation of nephron tubule epithelial cell differentiation [inference]

regulation of metanephric nephron tubule epithelial cell differentiation

regulation of multicellular organismal process [inference]

regulation of multicellular organismal development [inference]

regulation of epithelial cell differentiation [inference]

regulation of epithelial cell differentiation involved in kidney development [inference]

regulation of nephron tubule epithelial cell differentiation [inference]

regulation of metanephric nephron tubule epithelial cell differentiation

Displaying **all 2** entries
GO Term	Evidence Code	PMID
plasma membrane	IEA
apical part of cell	IDA	19506035

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

apical part of cell

Displaying **all 2** entries
GO Term	Evidence Code	PMID
calcium ion binding	IEA
protein binding	IPI	19506035

GO Hierarchy

molecular function

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

cadherin

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 2** entries
Gene Ontology
calcium ion binding
homophilic cell adhesion via plasma membrane adhesion molecules

Displaying **all 3** entries
InterPro
Cadherin conserved site
Cadherin-like superfamily
Cadherin-like

Ortholog

Displaying entries **1 - 10** of 82 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	33627	Xenbase:XB-GENE-981052
Homo sapiens	79633	Xenbase:XB-GENE-981052	HUMAN77291
Rattus norvegicus	310341		RATNO24780
Xenopus tropicalis	329628	Xenbase:XB-GENE-981052
Pan troglodytes	471300		PANTR34443
Canis lupus familiaris	483834		CANLF06273
Macaca mulatta	711867		MACMU37230
Bos taurus	781683		BOVIN09209
Equus caballus	100063659		HORSE28652
Taeniopygia guttata	100222872		TAEGU23609