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GO Term	Evidence Code	PMID
RNA binding	IDA	19158098
single-stranded RNA binding	IDA	22965130
protein binding	IPI	19299493
ATP binding	IDA	19158098
ATP-dependent activity, acting on DNA	IDA	19158098

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

catalytic activity, acting on a protein [inference]

ATP-dependent histone chaperone activity [inference]

catalytic activity, acting on a nucleic acid [inference]

helicase activity [inference]

DNA helicase activity

four-way junction helicase activity

single-stranded DNA helicase activity [inference]

single-stranded 3'-5' DNA helicase activity

double-stranded DNA helicase activity

3'-5' DNA helicase activity [inference]

single-stranded 3'-5' DNA helicase activity

RNA helicase activity [inference]

5'-3' RNA helicase activity

catalytic activity, acting on DNA [inference]

ATP-dependent activity, acting on DNA

DNA helicase activity

four-way junction helicase activity

single-stranded DNA helicase activity [inference]

single-stranded 3'-5' DNA helicase activity

double-stranded DNA helicase activity

3'-5' DNA helicase activity [inference]

single-stranded 3'-5' DNA helicase activity

DNA clamp loader activity

DNA translocase activity [inference]

chromatin extrusion motor activity

ATP-dependent chromatin remodeler activity [inference]

ATP-dependent histone chaperone activity [inference]

cohesin loader activity

catalytic activity, acting on RNA [inference]

RNA helicase activity [inference]

5'-3' RNA helicase activity

binding [inference]

protein binding

transcription factor binding

general transcription initiation factor binding

identical protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

protein-containing complex binding [inference]

ribonucleoprotein complex binding [inference]

ribosome binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding

single-stranded DNA binding

RNA binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

molecular carrier activity [inference]

protein carrier chaperone [inference]

histone chaperone activity [inference]

H3-H4 histone complex chaperone activity [inference]

ATP-dependent H3-H4 histone complex chaperone activity

ATP-dependent histone chaperone activity [inference]

ATP-dependent activity [inference]

helicase activity [inference]

DNA helicase activity

four-way junction helicase activity

single-stranded DNA helicase activity [inference]

single-stranded 3'-5' DNA helicase activity

double-stranded DNA helicase activity

3'-5' DNA helicase activity [inference]

single-stranded 3'-5' DNA helicase activity

RNA helicase activity [inference]

5'-3' RNA helicase activity

ATP-dependent activity, acting on DNA

DNA helicase activity

four-way junction helicase activity

single-stranded DNA helicase activity [inference]

single-stranded 3'-5' DNA helicase activity

double-stranded DNA helicase activity

3'-5' DNA helicase activity [inference]

single-stranded 3'-5' DNA helicase activity

DNA clamp loader activity

DNA translocase activity [inference]

chromatin extrusion motor activity

ATP-dependent chromatin remodeler activity [inference]

ATP-dependent histone chaperone activity [inference]

ATP-dependent activity, acting on RNA

RNA helicase activity [inference]

5'-3' RNA helicase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

helicase

Functional Category

K: Transcription
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying **all 4** entries
InterPro
DNA2/NAM7 helicase, helicase domain
DNA2/NAM7 helicase-like, C-terminal
P-loop containing nucleoside triphosphate hydrolase
Upf1-like, C-terminal helicase domain

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0110171	Charcot-Marie-Tooth disease axonal type 2S	Alliance of Genome Resources
DOID:0111064	autosomal recessive distal hereditary motor neuronopathy 1	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 66 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	3508	Xenbase:XB-GENE-6258282
Mus musculus	20589		MOUSE25459
Rattus norvegicus	29532		RATNO19087
Pan troglodytes	451384		PANTR03640
Canis lupus familiaris	483686		CANLF05952
Danio rerio	556484		DANRE14239
Bos taurus	618606		BOVIN23621
Macaca mulatta	721554		MACMU09086
Ciona intestinalis	751571		CIOIN04088
Equus caballus	100060088		HORSE05784