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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
keratin 2
Summary
- Gene Symbol
-
- KRT2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Coiled coil
- Cytoplasm
- Disease variant
- Ichthyosis
- Intermediate filament
- Keratin
- Methylation
- Phosphoprotein
- Reference proteome
- Proteins
| UniProt | Protein Name |
|---|---|
| P35908 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of epidermis development | ||
| keratinocyte proliferation | ||
| keratinocyte development | ||
| epidermis development | ||
| peptide cross-linking |
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| cornified envelope | ||
| keratin filament | ||
| intermediate filament | ||
| extracellular space |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| structural constituent of skin epidermis | ||
| structural constituent of cytoskeleton | ||
| cytoskeletal protein binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Keratin, type II
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- I: Lipid transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
| Gene Ontology |
|---|
| intermediate filament organization |
| keratinization |
| structural constituent of skin epidermis |
| InterPro |
|---|
| Intermediate filament protein, conserved site |
| Intermediate filament, rod domain |
| Keratin type II head |
| Keratin, type II |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060877 | bullous congenital ichthyosiform erythroderma | |
| DOID:1697 | ichthyosis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 797351 | ZFIN:ZDB-GENE-991110-23 | |||
| 100049665 | PIGXX25389 | |||
| 100458217 | 9601_0:003500 | PONAB06452 | ||
| 100489158 | Xenbase:XB-GENE-5840032 | |||
| 100491159 | Xenbase:XB-GENE-6035591 | |||
| 100596772 | NOMLE02958 | |||
| 100714514 | CAVPO05741 | |||
| 100752858 | CRIGR22962 | |||
| 100933339 | SARHA16872 | |||
| 100968804 | 9597_0:003395 | PANPA09325 |
