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Acetylcholine esterase

Summary

Gene Symbol

Ace

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

41625

KEGG Gene ID

PubChem

41625

Alliance of Genome Resources

FB:FBgn0000024

Annotation

Keyword

3D-structure
Cell membrane
Direct protein sequencing
Disulfide bond
GPI-anchor
Glycoprotein
Neurotransmitter degradation
Proteomics identification
Reference proteome
Serine esterase
Signal
Synapse

Proteins

Displaying **all 3** entries
UniProt	Protein Name
P07140
A0A0B4KGI5
E1JIJ8

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
acetylcholine catabolic process in synaptic cleft	IEA
acetylcholine catabolic process	IDA
acetylcholine catabolic process	IMP
acetylcholine catabolic process	IBA
chemical synaptic transmission	IMP

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

metabolic process [inference]

acetylcholine metabolic process [inference]

acetylcholine catabolic process

acetylcholine catabolic process in synaptic cleft

catabolic process [inference]

acetylcholine catabolic process

acetylcholine catabolic process in synaptic cleft

amine catabolic process [inference]

biogenic amine catabolic process [inference]

choline catabolic process

amine metabolic process [inference]

amine catabolic process [inference]

biogenic amine catabolic process [inference]

choline catabolic process

choline metabolic process

choline catabolic process

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

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GO Term	Evidence Code	PMID
extracellular region	IBA
obsolete extracellular space
cytoplasm	IDA
plasma membrane	IDA
plasma membrane	IBA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

cell junction [inference]

synapse

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
acetylcholinesterase activity	IDA
acetylcholinesterase activity	IMP
acetylcholinesterase activity	IBA
acetylcholinesterase activity	IEA
cholinesterase activity	IDA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity

hydrolase activity, acting on ester bonds [inference]

carboxylic ester hydrolase activity [inference]

cholinesterase activity

acetylcholinesterase activity

serine hydrolase activity

catalytic activity, acting on a protein [inference]

peptidase activity

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

sulfate binding

sulfur compound binding [inference]

sulfate binding

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
membrane	FB:FBrf0231198
plasma membrane	PMID:3141264
cytoplasm	PMID:3141264

Ortholog

Displaying **all 8** entries
Species	Gene ID	Alliance of Genome Resources
Homo sapiens	590	HGNC:983
Homo sapiens	43	HGNC:108
Danio rerio	114549	ZFIN:ZDB-GENE-010906-1
Mus musculus	12038	MGI:894278
Mus musculus	11423	MGI:87876
Rattus norvegicus	83817	RGD:69313
Caenorhabditis elegans	171905	WB:WBGene00000036
Caenorhabditis elegans	181706	WB:WBGene00000035