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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
protein C, inactivator of coagulation factors Va and VIIIa
Summary
- Gene Symbol
-
- PROC
- Organism
- Canis lupus familiaris (dog)
Annotation
- Keyword
-
- Blood coagulation
- Calcium
- Cleavage on pair of basic residues
- Disulfide bond
- EGF-like domain
- Endoplasmic reticulum
- Gamma-carboxyglutamic acid
- Glycoprotein
- Golgi apparatus
- Hydroxylation
- Reference proteome
- Repeat
- Secreted
- Serine protease
- Signal
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| Q28278 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| negative regulation of coagulation |
|
|
| positive regulation of establishment of endothelial barrier |
|
|
| negative regulation of inflammatory response |
|
|
| negative regulation of blood coagulation |
|
GO Hierarchy
biological process
biological regulation [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| Golgi apparatus |
|
|
| extracellular region | ||
| endoplasmic reticulum |
|
|
| extracellular space |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| calcium ion binding | ||
| serine-type endopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- serine protease
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
| Gene Ontology |
|---|
| hydrolase activity |
| proteolysis |
| serine-type endopeptidase activity |
| serine-type peptidase activity |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 125173176 | 61388_0:0024d3 | |||
| 125911704 | 29064_0:003b33 | |||
| 129503981 | 34880_0:000a51 | |||
| 131503872 | 61452_0:000910 | |||
| 131826892 | 9666_0:00116e | |||
| 132013980 | 77151_0:00112c |
