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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
protein C, inactivator of coagulation factors Va and VIIIa
Summary
- Gene Symbol
-
- PROC
- Organism
- Canis lupus familiaris (dog)
Annotation
- Keyword
-
- Blood coagulation
- Calcium
- Cleavage on pair of basic residues
- Disulfide bond
- EGF-like domain
- Endoplasmic reticulum
- Gamma-carboxyglutamic acid
- Glycoprotein
- Golgi apparatus
- Hydroxylation
- Reference proteome
- Repeat
- Secreted
- Serine protease
- Signal
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| Q28278 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| negative regulation of coagulation |
|
|
| positive regulation of establishment of endothelial barrier |
|
|
| negative regulation of inflammatory response |
|
|
| negative regulation of blood coagulation |
|
GO Hierarchy
biological process
biological regulation [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| Golgi apparatus |
|
|
| extracellular region | ||
| endoplasmic reticulum |
|
|
| extracellular space |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| calcium ion binding | ||
| serine-type endopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- serine protease
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
| Gene Ontology |
|---|
| hydrolase activity |
| proteolysis |
| serine-type endopeptidase activity |
| serine-type peptidase activity |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 108533003 | RHIBE15689 | |||
| 109278799 | 9691_0:0003a3 | |||
| 109315280 | CROPO23662 | |||
| 110194676 | PHACI02395 | |||
| 110585784 | 29088_0:000d16 | |||
| 111160850 | 391180_0:00416a | |||
| 112652444 | 286419_0:003307 | |||
| 112811269 | 34884_0:00066e | |||
| 112865529 | 9696_0:0006ed | |||
| 112932724 | 9627_0:00354f | VULVU28487 |
