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opioid receptor kappa 1
Summary
- Gene Symbol
-
- OPRK1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Behavior
- Cell membrane
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Palmitate
- Proteomics identification
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| P41145 |
|
| A0A5F9ZI09 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| immune response | ||
| adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway | ||
| phospholipase C-activating G protein-coupled receptor signaling pathway | ||
| neuropeptide signaling pathway | ||
| chemical synaptic transmission |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| dendrite | ||
| synaptic vesicle membrane | ||
| presynaptic membrane | ||
| neuron projection | ||
| perikaryon |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| G protein-coupled opioid receptor activity | ||
| protein binding | ||
| receptor serine/threonine kinase binding | ||
| dynorphin receptor activity | ||
| dynorphin receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- G_PROTEIN_RECEP_F1_2 domain-containing protein
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| G protein-coupled opioid receptor activity |
| G protein-coupled opioid receptor signaling pathway |
| neuropeptide binding |
| neuropeptide signaling pathway |
| InterPro |
|---|
| G protein-coupled receptor, rhodopsin-like |
| GPCR, rhodopsin-like, 7TM |
| Opioid receptor |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050741 | alcohol dependence | |
| DOID:11206 | opioid abuse | |
| DOID:1574 | alcohol use disorder | |
| DOID:1596 | depressive disorder | |
| DOID:2559 | opiate dependence | |
| DOID:9828 | neonatal abstinence syndrome | |
| DOID:9975 | cocaine dependence | |
| DOID:9976 | heroin dependence |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 24613 | FB:FBgn0036789 | ||
| 25033 | FB:FBgn0036789 | ||
| 25555 | FB:FBgn0036789 | ||
| 25601 | FB:FBgn0036789 | ||
| 29256 | WB:WBGene00020086 | ||
| 29335 | Xenbase:XB-GENE-1011503 | RATNO34724 | |
| 54305 | FB:FBgn0036789 | ||
| 83567 | WB:WBGene00020086 | ||
| 171044 | FB:FBgn0036789 | ||
| 226304 | WB:WBGene00020086 |
