GlyCosmos Portal

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GO Term	Evidence Code	PMID
fatty acid synthase activity	ISO
fatty acid synthase activity	IDA	15715522 18062843 21389266 21569266
fatty acid synthase activity	IBA
fatty acid synthase activity	IEA
[acyl-carrier-protein] S-acetyltransferase activity	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity

transferase activity [inference]

acyltransferase activity [inference]

acyltransferase activity, transferring groups other than amino-acyl groups [inference]

acetyltransferase activity [inference]

S-acetyltransferase activity [inference]

[acyl-carrier-protein] S-acetyltransferase activity

S-acyltransferase activity [inference]

S-acetyltransferase activity [inference]

[acyl-carrier-protein] S-acetyltransferase activity

S-malonyltransferase activity [inference]

[acyl-carrier-protein] S-malonyltransferase activity

malonyltransferase activity [inference]

S-malonyltransferase activity [inference]

[acyl-carrier-protein] S-malonyltransferase activity

hydrolase activity

hydrolase activity, acting on ester bonds [inference]

thiolester hydrolase activity [inference]

acyl-[acyl-carrier-protein] hydrolase activity

lyase activity

carbon-oxygen lyase activity [inference]

hydro-lyase activity [inference]

(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity

binding [inference]

protein binding

identical protein binding

amide binding [inference]

phosphopantetheine binding

small molecule binding

vitamin binding [inference]

phosphopantetheine binding

modified amino acid binding [inference]

phosphopantetheine binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

polyketide synthase

Functional Category

I: Lipid transport and metabolism
J: Translation, ribosomal structure and biogenesis
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 4** entries
Gene Ontology
fatty acid synthase activity
oxidoreductase activity
phosphopantetheine binding
transferase activity

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InterPro
ACP-like superfamily
Acyl transferase domain superfamily
Acyl transferase/acyl hydrolase/lysophospholipase
Acyl transferase
Beta-ketoacyl synthase, C-terminal
Beta-ketoacyl synthase, N-terminal
Beta-ketoacyl synthase, active site
GroES-like superfamily
Malonyl-CoA ACP transacylase, ACP-binding
NAD(P)-binding domain superfamily

Rhea

RHEA:14993

H⁺ + acetyl-CoA + malonyl-CoA + NADPH

CO₂ + CoA + a long-chain fatty acid + NADP⁺

Enzyme

2.3.1.85

PMID

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP012642
Gene Name: fatty acid synthase

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	2194	Xenbase:XB-GENE-1002983	HUMAN37215
Mus musculus	14104	Xenbase:XB-GENE-1002983	MOUSE05379
Xenopus tropicalis	50671	Xenbase:XB-GENE-1002983
Bos taurus	281152		BOVIN13729
Danio rerio	284001	ZFIN:ZDB-GENE-090603-1
Sus scrofa	397561		PIGXX01624
Pan troglodytes	454986		PANTR15736
Canis lupus familiaris	483378		CANLF18324
Macaca mulatta	715708		MACMU14122
Monodelphis domestica	100025176		MONDO10804

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements