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cytochrome P450 family 2 subfamily W member 1

Summary

Gene Symbol

CYP2W1

Organism

Homo sapiens (human)

External Links

NCBI Gene

54905

PubChem

54905

Alliance of Genome Resources

HGNC:20243

Annotation

Keyword

Cell membrane
Glycoprotein
Heme
Lipid metabolism
Microsome
Monooxygenase
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8TAV3	CYPIIW1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
organic acid metabolic process	IBA
phospholipid metabolic process	IDA	22591743
xenobiotic metabolic process	IDA	16551781
xenobiotic metabolic process	IBA
retinoic acid catabolic process	IDA	26936974

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

cytochrome metabolic process

catabolic process [inference]

cellular catabolic process [inference]

vitamin catabolic process [inference]

fat-soluble vitamin catabolic process [inference]

retinoic acid catabolic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

retinoic acid catabolic process

cellular lipid catabolic process [inference]

isoprenoid catabolic process [inference]

terpenoid catabolic process [inference]

diterpenoid catabolic process [inference]

retinoic acid catabolic process

small molecule catabolic process [inference]

vitamin catabolic process [inference]

fat-soluble vitamin catabolic process [inference]

retinoic acid catabolic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

retinoic acid catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

isoprenoid catabolic process [inference]

terpenoid catabolic process [inference]

diterpenoid catabolic process [inference]

retinoic acid catabolic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

retinoic acid catabolic process

secondary metabolic process [inference]

toxin metabolic process [inference]

mycotoxin metabolic process [inference]

aflatoxin metabolic process

hormone metabolic process [inference]

retinoic acid metabolic process [inference]

retinoic acid catabolic process

cellular metabolic process [inference]

organic acid metabolic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

retinoic acid catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

retinoic acid metabolic process [inference]

retinoic acid catabolic process

monocarboxylic acid catabolic process [inference]

retinoic acid catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

retinoic acid catabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process

xenobiotic metabolic process

toxin metabolic process [inference]

mycotoxin metabolic process [inference]

aflatoxin metabolic process

cellular catabolic process [inference]

vitamin catabolic process [inference]

fat-soluble vitamin catabolic process [inference]

retinoic acid catabolic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

retinoic acid catabolic process

cellular lipid catabolic process [inference]

isoprenoid catabolic process [inference]

terpenoid catabolic process [inference]

diterpenoid catabolic process [inference]

retinoic acid catabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process [inference]

retinoic acid metabolic process [inference]

retinoic acid catabolic process

diterpenoid catabolic process [inference]

retinoic acid catabolic process

terpenoid catabolic process [inference]

diterpenoid catabolic process [inference]

retinoic acid catabolic process

isoprenoid catabolic process [inference]

terpenoid catabolic process [inference]

diterpenoid catabolic process [inference]

retinoic acid catabolic process

cellular lipid catabolic process [inference]

isoprenoid catabolic process [inference]

terpenoid catabolic process [inference]

diterpenoid catabolic process [inference]

retinoic acid catabolic process

heterocycle metabolic process [inference]

organic heteropentacyclic compound metabolic process [inference]

aflatoxin metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

isoprenoid catabolic process [inference]

terpenoid catabolic process [inference]

diterpenoid catabolic process [inference]

retinoic acid catabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process [inference]

retinoic acid metabolic process [inference]

retinoic acid catabolic process

diterpenoid catabolic process [inference]

retinoic acid catabolic process

terpenoid catabolic process [inference]

diterpenoid catabolic process [inference]

retinoic acid catabolic process

isoprenoid catabolic process [inference]

terpenoid catabolic process [inference]

diterpenoid catabolic process [inference]

retinoic acid catabolic process

cellular lipid catabolic process [inference]

isoprenoid catabolic process [inference]

terpenoid catabolic process [inference]

diterpenoid catabolic process [inference]

retinoic acid catabolic process

protein metabolic process [inference]

cytochrome metabolic process

small molecule metabolic process [inference]

organic acid metabolic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

retinoic acid catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

retinoic acid metabolic process [inference]

retinoic acid catabolic process

monocarboxylic acid catabolic process [inference]

retinoic acid catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

retinoic acid catabolic process

vitamin metabolic process [inference]

fat-soluble vitamin metabolic process [inference]

fat-soluble vitamin catabolic process [inference]

retinoic acid catabolic process

vitamin catabolic process [inference]

fat-soluble vitamin catabolic process [inference]

retinoic acid catabolic process

small molecule catabolic process [inference]

vitamin catabolic process [inference]

fat-soluble vitamin catabolic process [inference]

retinoic acid catabolic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

retinoic acid catabolic process

organic substance metabolic process [inference]

organic acid metabolic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

retinoic acid catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

retinoic acid metabolic process [inference]

retinoic acid catabolic process

monocarboxylic acid catabolic process [inference]

retinoic acid catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

retinoic acid catabolic process

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

isoprenoid catabolic process [inference]

terpenoid catabolic process [inference]

diterpenoid catabolic process [inference]

retinoic acid catabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process [inference]

retinoic acid metabolic process [inference]

retinoic acid catabolic process

diterpenoid catabolic process [inference]

retinoic acid catabolic process

terpenoid catabolic process [inference]

diterpenoid catabolic process [inference]

retinoic acid catabolic process

isoprenoid catabolic process [inference]

terpenoid catabolic process [inference]

diterpenoid catabolic process [inference]

retinoic acid catabolic process

cellular lipid catabolic process [inference]

isoprenoid catabolic process [inference]

terpenoid catabolic process [inference]

diterpenoid catabolic process [inference]

retinoic acid catabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

cytochrome metabolic process

organic cyclic compound metabolic process [inference]

organic heteropentacyclic compound metabolic process [inference]

aflatoxin metabolic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

cytochrome metabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

isoprenoid catabolic process [inference]

terpenoid catabolic process [inference]

diterpenoid catabolic process [inference]

retinoic acid catabolic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

retinoic acid catabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

retinoic acid catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

retinoic acid metabolic process [inference]

retinoic acid catabolic process

monocarboxylic acid catabolic process [inference]

retinoic acid catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

retinoic acid catabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process

xenobiotic metabolic process

toxin metabolic process [inference]

mycotoxin metabolic process [inference]

aflatoxin metabolic process

cellular catabolic process [inference]

vitamin catabolic process [inference]

fat-soluble vitamin catabolic process [inference]

retinoic acid catabolic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

retinoic acid catabolic process

cellular lipid catabolic process [inference]

isoprenoid catabolic process [inference]

terpenoid catabolic process [inference]

diterpenoid catabolic process [inference]

retinoic acid catabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process [inference]

retinoic acid metabolic process [inference]

retinoic acid catabolic process

diterpenoid catabolic process [inference]

retinoic acid catabolic process

terpenoid catabolic process [inference]

diterpenoid catabolic process [inference]

retinoic acid catabolic process

isoprenoid catabolic process [inference]

terpenoid catabolic process [inference]

diterpenoid catabolic process [inference]

retinoic acid catabolic process

cellular lipid catabolic process [inference]

isoprenoid catabolic process [inference]

terpenoid catabolic process [inference]

diterpenoid catabolic process [inference]

retinoic acid catabolic process

heterocycle metabolic process [inference]

organic heteropentacyclic compound metabolic process [inference]

aflatoxin metabolic process

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

retinoic acid metabolic process [inference]

retinoic acid catabolic process

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
cytoplasm	IBA
endoplasmic reticulum lumen	IDA	20805301
endoplasmic reticulum membrane	TAS
plasma membrane	IEA
cell surface	IDA	20805301

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

intracellular organelle [inference]

intracellular membrane-bounded organelle

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
retinoic acid binding	IDA	26936974
monooxygenase activity	TAS
all-trans retinal binding	IDA	26936974
iron ion binding	IEA
retinoic acid 4-hydroxylase activity	IDA	26936974

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

monooxygenase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

binding [inference]

lipid binding [inference]

isoprenoid binding [inference]

retinoid binding [inference]

retinoic acid binding

retinal binding [inference]

all-trans retinal binding

retinol binding [inference]

all-trans-retinol binding

small molecule binding [inference]

vitamin binding [inference]

retinal binding [inference]

all-trans retinal binding

retinol binding [inference]

all-trans-retinol binding

organic acid binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

retinoic acid binding

alcohol binding [inference]

retinol binding [inference]

all-trans-retinol binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

retinoic acid binding

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding

organic cyclic compound binding [inference]

tetrapyrrole binding [inference]

heme binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Cytochrome P450

Functional Category

C: Energy production and conversion
I: Lipid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
heme binding
iron ion binding
metal ion binding
monooxygenase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
oxidoreductase activity

Displaying **all 4** entries
InterPro
Cytochrome P450 superfamily
Cytochrome P450, E-class, group I
Cytochrome P450, conserved site
Cytochrome P450

Ortholog

Displaying entries **1 - 10** of 62 in total

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Species	Gene ID	Alliance of Genome Resources
Drosophila melanogaster	1555	FB:FBgn0036910
Caenorhabditis elegans	1557	WB:WBGene00019472
Caenorhabditis elegans	1558	WB:WBGene00019472
Caenorhabditis elegans	1559	WB:WBGene00019472
Caenorhabditis elegans	1562	WB:WBGene00019472
Caenorhabditis elegans	1564	WB:WBGene00019565
Caenorhabditis elegans	1571	WB:WBGene00019565
Drosophila melanogaster	1573	FB:FBgn0036910
Caenorhabditis elegans	13085	WB:WBGene00019565
Caenorhabditis elegans	13086	WB:WBGene00019565

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Acknowledgements