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MIRAGE
Rac family small GTPase 2
Summary
- Gene Symbol
-
- RAC2
- Organism
- Homo sapiens (human)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| chemotaxis | ||
| actin filament organization | ||
| actin filament organization | ||
| establishment or maintenance of cell polarity | ||
| signal transduction |
GO Hierarchy
biological process
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of localization [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| nuclear envelope | ||
| mitochondrial outer membrane | ||
| endoplasmic reticulum membrane | ||
| cytosol | ||
| cytosol |
| GO Term | Evidence Code | PMID |
|---|---|---|
| GTPase activity | ||
| protein binding | ||
| GTP binding | ||
| GTP binding | ||
| protein kinase regulator activity |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- GTPase
- Functional Category
-
- T: Signal transduction mechanisms
- U: Intracellular trafficking, secretion, and vesicular transport
| Gene Ontology |
|---|
| GTP binding |
| nucleotide binding |
| protein kinase binding |
| small GTPase-mediated signal transduction |
| InterPro |
|---|
| P-loop containing nucleoside triphosphate hydrolase |
| Small GTP-binding protein domain |
| Small GTPase Rho |
| Small GTPase |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0112061 | immunodeficiency 73b with defective neutrophil chemotaxis and lymphopenia | |
| DOID:0112062 | immunodeficiency 73c with defective neutrophil chemotaxis and hypogammaglobulinemia | |
| DOID:0112064 | immunodeficiency 73a with defective neutrophil chemotaxis and leukocytosis |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 5879 | FB:FBgn0014011 | ||
| 5880 | Xenbase:XB-GENE-494950 | ||
| 5881 | FB:FBgn0014011 | ||
| 19354 | MOUSE16777 | ||
| 327671 | BOVIN29979 | ||
| 481271 | CANLF01645 | ||
| 696709 | MACMU00605 | ||
| 742575 | PANTR26496 | ||
| 100230090 | TAEGU09205 | ||
| 100395636 | CALJA20935 |
