Rac family small GTPase 2
| GO Term | Evidence Code | PMID |
|---|---|---|
| G protein-coupled receptor signaling pathway | ||
| small GTPase mediated signal transduction | ||
| regulation of cell shape | ||
| regulation of hydrogen peroxide metabolic process | ||
| positive regulation of lamellipodium assembly |
| GO Term | Evidence Code | PMID |
|---|---|---|
| nuclear envelope | ||
| mitochondrial outer membrane | ||
| endoplasmic reticulum membrane | ||
| cytosol | ||
| cytosol |
| GO Term | Evidence Code | PMID |
|---|---|---|
| GTPase activity | ||
| protein binding | ||
| GTP binding | ||
| GTP binding | ||
| protein kinase regulator activity |
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0112061 | immunodeficiency 73b with defective neutrophil chemotaxis and lymphopenia | |
| DOID:0112062 | immunodeficiency 73c with defective neutrophil chemotaxis and hypogammaglobulinemia | |
| DOID:0112064 | immunodeficiency 73a with defective neutrophil chemotaxis and leukocytosis |
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Partly supported by NIH Common Fund Grant #1U01GM125267-01
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Last updated: April 6, 2026