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sodium voltage-gated channel beta subunit 2

Summary

Gene Symbol

SCN2B

Organism

Homo sapiens (human)

External Links

NCBI Gene

6327

PubChem

6327

Alliance of Genome Resources

HGNC:10589

JoGo

SCN2B

TogoVar

SCN2B

Annotation

Keyword

3D-structure
Atrial fibrillation
Brugada syndrome
Cell membrane
Cell projection
Disease variant
Disulfide bond
Glycoprotein
Immunoglobulin domain
Ion channel
Phosphoprotein
Proteomics identification
Reference proteome
Signal
Sodium transport
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
O60939
Q5U0K8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
chemical synaptic transmission	TAS	9295116
nervous system development	IEA
response to heat	IEA
gene expression	IEA
positive regulation of sodium ion transport	IDA	19808477

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

multicellular organismal process [inference]

system process [inference]

muscle system process [inference]

muscle contraction [inference]

striated muscle contraction [inference]

cardiac muscle contraction

developmental process [inference]

anatomical structure development [inference]

system development [inference]

nervous system development

response to stimulus [inference]

response to stress [inference]

response to heat

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

response to heat

response to chemical [inference]

response to toxic substance [inference]

response to insecticide [inference]

response to pyrethroid

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport [inference]

sodium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

regulation of localization [inference]

regulation of transport [inference]

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of sodium ion transport [inference]

positive regulation of sodium ion transport

positive regulation of monoatomic ion transport [inference]

positive regulation of sodium ion transport

positive regulation of transport [inference]

positive regulation of monoatomic ion transport [inference]

positive regulation of sodium ion transport

positive regulation of biological process [inference]

positive regulation of transport [inference]

positive regulation of monoatomic ion transport [inference]

positive regulation of sodium ion transport

regulation of cellular process [inference]

regulation of membrane depolarization [inference]

regulation of atrial cardiac muscle cell membrane depolarization

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of blood circulation [inference]

regulation of heart contraction [inference]

regulation of heart rate [inference]

regulation of heart rate by cardiac conduction

cardiac conduction

regulation of heart rate by cardiac conduction

regulation of biological quality [inference]

regulation of heart rate [inference]

regulation of heart rate by cardiac conduction

regulation of membrane potential [inference]

action potential [inference]

cardiac muscle cell action potential [inference]

cardiac muscle cell action potential involved in contraction

regulation of membrane depolarization [inference]

regulation of atrial cardiac muscle cell membrane depolarization

membrane depolarization [inference]

membrane depolarization during action potential

membrane depolarization during cardiac muscle cell action potential

membrane repolarization [inference]

membrane repolarization during action potential [inference]

membrane repolarization during cardiac muscle cell action potential [inference]

membrane repolarization during ventricular cardiac muscle cell action potential

cardiac muscle cell membrane repolarization [inference]

membrane repolarization during cardiac muscle cell action potential [inference]

membrane repolarization during ventricular cardiac muscle cell action potential

ventricular cardiac muscle cell membrane repolarization [inference]

membrane repolarization during ventricular cardiac muscle cell action potential

Displaying entries **6 - 9** of 9 in total

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GO Term	Evidence Code	PMID
T-tubule	IEA
node of Ranvier	IEA
axon initial segment	IEA
synapse	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

voltage-gated sodium channel complex

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

sodium channel complex [inference]

voltage-gated sodium channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

sodium channel complex [inference]

voltage-gated sodium channel complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

cell junction [inference]

synapse

Displaying **all 4** entries
GO Term	Evidence Code	PMID
sodium channel regulator activity	IDA	19808477
sodium channel regulator activity	IBA
voltage-gated sodium channel activity involved in cardiac muscle cell action potential	IEA
voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	IEA