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MIRAGE
piezo type mechanosensitive ion channel component 2
Summary
- Gene Symbol
-
- PIEZO2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Coiled coil
- Disease variant
- Disulfide bond
- Glycoprotein
- Ion channel
- Phosphoprotein
- Reference proteome
- Sensory transduction
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9H5I5 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| monoatomic cation transport | ||
| response to mechanical stimulus | ||
| regulation of membrane potential | ||
| detection of mechanical stimulus involved in sensory perception | ||
| detection of mechanical stimulus |
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| stereocilium | ||
| cuticular plate | ||
| neuronal cell body membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| monoatomic cation channel activity | ||
| mechanosensitive monoatomic ion channel activity | ||
| mechanosensitive monoatomic ion channel activity | ||
| mechanosensitive monoatomic cation channel activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Piezo-type mechanosensitive ion channel component
- Functional Category
-
- I: Lipid transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| InterPro |
|---|
| Piezo family |
| Piezo non-specific cation channel, R-Ras-binding domain |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0111607 | distal arthrogryposis type 3 | |
| DOID:0111608 | distal arthrogryposis type 5 |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 9780 | FB:FBgn0264953 | ||
| 63895 | FB:FBgn0264953 | ||
| 182492 | FB:FBgn0264953 | ||
| 234839 | FB:FBgn0264953 | ||
| 307380 | RATNO13779 | ||
| 361430 | FB:FBgn0267430 | ||
| 455495 | PANTR15854 | ||
| 490554 | CANLF17653 | ||
| 667742 | FB:FBgn0264953 | MOUSE23525 | |
| 100017409 | MONDO18909 |
