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atlastin GTPase 2

Summary

Gene Symbol

ATL2

Aliases

Atlastin-2
atlastin2

Organism

Homo sapiens (human)

External Links

NCBI Gene

64225

HGNC

24047

PubChem

64225

Alliance of Genome Resources

HGNC:24047

Annotation

Keyword

Alternative splicing
Coiled coil
Endoplasmic reticulum
GTP-binding
Hydrolase
Methylation
Phosphoprotein
Proteomics identification
Reference proteome
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
B5MCN0
Q8NHH9	ADP-ribosylation factor-like protein 6-interacting protein 2
B7Z2H0

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
endoplasmic reticulum to Golgi vesicle-mediated transport	IMP	18270207
endoplasmic reticulum organization	IMP	18270207 19665976
endoplasmic reticulum organization	IBA
Golgi organization	IMP	18270207
protein homooligomerization	IDA	18270207

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport [inference]

Golgi vesicle transport [inference]

endoplasmic reticulum to Golgi vesicle-mediated transport

cellular localization [inference]

intracellular transport [inference]

endoplasmic reticulum to Golgi vesicle-mediated transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

endoplasmic reticulum organization

endoplasmic reticulum tubular network organization [inference]

endoplasmic reticulum tubular network membrane organization

Golgi organization

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization

membrane organization [inference]

endoplasmic reticulum membrane organization [inference]

endoplasmic reticulum tubular network membrane organization

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

Golgi vesicle transport [inference]

endoplasmic reticulum to Golgi vesicle-mediated transport

intracellular transport [inference]

endoplasmic reticulum to Golgi vesicle-mediated transport

establishment of localization in cell [inference]

intracellular transport [inference]

endoplasmic reticulum to Golgi vesicle-mediated transport

cellular localization [inference]

intracellular transport [inference]

endoplasmic reticulum to Golgi vesicle-mediated transport

Displaying **all 4** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum	IDA	18270207
membrane	IDA	18270207
membrane	HDA	19946888
endoplasmic reticulum tubular network membrane	IDA	27619977

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane [inference]

endoplasmic reticulum tubular network membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 5** entries
GO Term	Evidence Code	PMID
GTPase activity	NAS	18270207
GTPase activity	IBA
protein binding	IPI	15161933 19665976 23969831 35271311
GTP binding	IBA
identical protein binding	IDA	18270207

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

GTPase activity

binding [inference]

protein binding

identical protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

GTP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

atlastin

Functional Category

J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
GTP binding
endoplasmic reticulum organization
protein homooligomerization

Displaying **all 4** entries
InterPro
GB1/RHD3-type guanine nucleotide-binding (G) domain
Guanylate-binding protein, C-terminal domain superfamily
Guanylate-binding protein, N-terminal
P-loop containing nucleoside triphosphate hydrolase

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	25923	FB:FBgn0039213
Mus musculus	56298		MOUSE22057
Xenopus tropicalis	64225	Xenbase:XB-GENE-947235
Drosophila melanogaster	109168	FB:FBgn0039213
Rattus norvegicus	298757		RATNO34954
Pan troglodytes	459164		PANTR27434
Macaca mulatta	710647		MACMU08764
Monodelphis domestica	100011436		MONDO08014
Bos taurus	100140212		BOVIN02263
Ciona intestinalis	100183306		CIOIN12699

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OrthoDB (Group)

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Acknowledgements