GlyCosmos Portal

Annotation

Keyword

Disulfide bond
Glycoprotein
Glycosyltransferase
Golgi apparatus
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q5JCT0	C2GnT-mucin type Mucus-type core 2 beta-1,6-N-acetylglucosaminyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
intestinal absorption	IMP	19349303
immunoglobulin production in mucosal tissue	IMP	19349303
kidney morphogenesis	IGI	19349303
protein O-linked glycosylation	ISO
tissue morphogenesis	IGI	19349303

GO Hierarchy

biological process

immune system process [inference]

production of molecular mediator of immune response [inference]

immunoglobulin production [inference]

immunoglobulin production involved in immunoglobulin-mediated immune response [inference]

immunoglobulin production in mucosal tissue

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

production of molecular mediator of immune response [inference]

immunoglobulin production [inference]

immunoglobulin production involved in immunoglobulin-mediated immune response [inference]

immunoglobulin production in mucosal tissue

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

production of molecular mediator of immune response [inference]

immunoglobulin production [inference]

immunoglobulin production involved in immunoglobulin-mediated immune response [inference]

immunoglobulin production in mucosal tissue

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

production of molecular mediator of immune response [inference]

immunoglobulin production [inference]

immunoglobulin production involved in immunoglobulin-mediated immune response [inference]

immunoglobulin production in mucosal tissue

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

production of molecular mediator of immune response [inference]

immunoglobulin production [inference]

immunoglobulin production involved in immunoglobulin-mediated immune response [inference]

immunoglobulin production in mucosal tissue

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

production of molecular mediator of immune response [inference]

immunoglobulin production [inference]

immunoglobulin production involved in immunoglobulin-mediated immune response [inference]

immunoglobulin production in mucosal tissue

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

production of molecular mediator of immune response [inference]

immunoglobulin production [inference]

immunoglobulin production involved in immunoglobulin-mediated immune response [inference]

immunoglobulin production in mucosal tissue

multicellular organismal process [inference]

system process [inference]

digestive system process [inference]

intestinal absorption

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

kidney morphogenesis

tissue morphogenesis

localization [inference]

establishment of localization [inference]

transport [inference]

intestinal absorption

Displaying 1 entry
GO Term	Evidence Code	PMID
Golgi membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity	IEA
acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity	IMP	19349303
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity	IEA ISO
acetylgalactosaminyl-O-glycosyl-threonyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity
acetylglucosaminyltransferase activity	IBA ISO

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity

acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity

acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity

catalytic activity, acting on a protein [inference]

catalytic activity, acting on a glycoprotein [inference]

beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity

acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
acetylglucosaminyltransferase activity
transferase activity

Displaying 1 entry
InterPro
Glycosyl transferase, family 14

KEGG BRITE Database

Orthology

K09662

Name

N-acetylglucosaminyltransferase 3, mucin type [EC:2.4.1.-]

References

9915862

Reactions

Displaying **all 2** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05915	2.4.1.148	G00035MO	G00037MO
R05912	2.4.1.102	G00031MO	G00033MO

Rhea

RHEA:56212

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.102

PMID

RHEA:56188

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.148

PMID

RHEA:54820

a β-D-Gal-(1→4)-β-D-GlcNAc-(1→3)-β-D-Gal-(1→4)-β-D-GlcNAc derivative + UDP-N-acetyl-α-D-glucosamine

a β-D-Gal-(1→4)-β-D-GlcNAc-(1→3)-[β-D-GlcNAc-(1→6)]-β-D-Gal-(1→4)-N-acetyl-β-D-glucosaminyl derivative + H⁺ + UDP

Enzyme

2.4.1.150

PMID

RHEA:56192

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.148

PMID

RHEA:17413

a β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl derivative + UDP-N-acetyl-α-D-glucosamine

an N-acetyl-β-D-glucosaminyl-(1→6)-β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl derivative + H⁺ + UDP

Enzyme

2.4.1.150

PMID

RHEA:56216

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.102

PMID

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP005157
Gene Name: glucosaminyl (N-acetyl) transferase 3, mucin type

Ortholog

Displaying entries **1 - 10** of **133** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	9245		HGNC:4205	HUMAN23386
Caenorhabditis elegans	172446		WB:WBGene00001643
Caenorhabditis elegans	172447		WB:WBGene00001644
Caenorhabditis elegans	173108		WB:WBGene00001642
Caenorhabditis elegans	173109		WB:WBGene00001641
Caenorhabditis elegans	173114		WB:WBGene00001640
Caenorhabditis elegans	174679		WB:WBGene00001626
Rattus norvegicus	286976	10116_1:002f76	RGD:631333	RATNO40280
Bos taurus	404167			BOVIN01255
Pan troglodytes	453482			PANTR10451

GlyTouCan

GlyComb

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UniCarb-DR

LM-GlycoRepo

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Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements