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glucosaminyl (N-acetyl) transferase 3, mucin type

Summary

Gene Symbol

Gcnt3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

72077

KEGG Gene ID

mmu:72077

PubChem

72077

Alliance of Genome Resources

MGI:1919327

Annotation

Keyword

Disulfide bond
Glycoprotein
Glycosyltransferase
Golgi apparatus
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q5JCT0	C2GnT-mucin type Mucus-type core 2 beta-1,6-N-acetylglucosaminyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
intestinal absorption	IMP	19349303
immunoglobulin production in mucosal tissue	IMP	19349303
kidney morphogenesis	IGI	19349303
protein O-linked glycosylation	ISO
tissue morphogenesis	IGI	19349303

GO Hierarchy

biological process

immune system process [inference]

production of molecular mediator of immune response [inference]

immunoglobulin production [inference]

immunoglobulin production involved in immunoglobulin-mediated immune response [inference]

immunoglobulin production in mucosal tissue

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

production of molecular mediator of immune response [inference]

immunoglobulin production [inference]

immunoglobulin production involved in immunoglobulin-mediated immune response [inference]

immunoglobulin production in mucosal tissue

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

production of molecular mediator of immune response [inference]

immunoglobulin production [inference]

immunoglobulin production involved in immunoglobulin-mediated immune response [inference]

immunoglobulin production in mucosal tissue

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

production of molecular mediator of immune response [inference]

immunoglobulin production [inference]

immunoglobulin production involved in immunoglobulin-mediated immune response [inference]

immunoglobulin production in mucosal tissue

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

production of molecular mediator of immune response [inference]

immunoglobulin production [inference]

immunoglobulin production involved in immunoglobulin-mediated immune response [inference]

immunoglobulin production in mucosal tissue

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

production of molecular mediator of immune response [inference]

immunoglobulin production [inference]

immunoglobulin production involved in immunoglobulin-mediated immune response [inference]

immunoglobulin production in mucosal tissue

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

production of molecular mediator of immune response [inference]

immunoglobulin production [inference]

immunoglobulin production involved in immunoglobulin-mediated immune response [inference]

immunoglobulin production in mucosal tissue

multicellular organismal process [inference]

system process [inference]

digestive system process [inference]

intestinal absorption

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

kidney morphogenesis

tissue morphogenesis

localization [inference]

establishment of localization [inference]

transport [inference]

intestinal absorption

Displaying 1 entry
GO Term	Evidence Code	PMID
Golgi membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity	IEA
acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity	IMP	19349303
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity	IEA ISO
acetylgalactosaminyl-O-glycosyl-threonyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity
acetylglucosaminyltransferase activity	IBA ISO

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity

acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity

acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity

catalytic activity, acting on a protein [inference]

catalytic activity, acting on a glycoprotein [inference]

beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity

acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
acetylglucosaminyltransferase activity
transferase activity

Displaying 1 entry
InterPro
Glycosyl transferase, family 14

KEGG BRITE Database

Orthology

K09662

Name

N-acetylglucosaminyltransferase 3, mucin type [EC:2.4.1.-]

References

9915862

Reactions

Displaying **all 2** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05915	2.4.1.148	G00035MO	G00037MO
R05912	2.4.1.102	G00031MO	G00033MO

Rhea

RHEA:56212

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.102

PMID

RHEA:56188

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.148

PMID

RHEA:54820

a β-D-Gal-(1→4)-β-D-GlcNAc-(1→3)-β-D-Gal-(1→4)-β-D-GlcNAc derivative + UDP-N-acetyl-α-D-glucosamine

a β-D-Gal-(1→4)-β-D-GlcNAc-(1→3)-[β-D-GlcNAc-(1→6)]-β-D-Gal-(1→4)-N-acetyl-β-D-glucosaminyl derivative + H⁺ + UDP

Enzyme

2.4.1.150

PMID

RHEA:56192

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.148

PMID

RHEA:17413

a β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl derivative + UDP-N-acetyl-α-D-glucosamine

an N-acetyl-β-D-glucosaminyl-(1→6)-β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl derivative + H⁺ + UDP

Enzyme

2.4.1.150

PMID

RHEA:56216

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.102

PMID

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP005157
Gene Name: glucosaminyl (N-acetyl) transferase 3, mucin type

Ortholog

Displaying entries **101 - 110** of **133** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Salmo trutta	115193003		SALTR30309
Salmo trutta	115197746		SALTR11504
Salmo trutta	115207120		SALTR36646
Salarias fasciatus	115392416		SALFA29365
Salarias fasciatus	115392417		SALFA29365
Gadus morhua	115551135		GADMO62079
Sparus aurata	115586696		SPAAU45646
Mastomys coucha	116072720	35658_0:00360e
Chelonoidis abingdonii	116835588		CHEAB09421
Rattus rattus	116907412	10117_0:0034da

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements