GlyCosmos Portal

GlyTouCan

Glycan Structure Repository

GlyComb

Glycoconjugate Repository

GlycoPOST

Glycomics MS raw data Repository

UniCarb-DR

Glycomics MS Repository for glycan annotations from GlycoWorkbench

LM-GlycoRepo

Repository for lectin-assisted multimodality data

All Resources

Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms

Other Information

Release Statistics Download

Tools

Glycan Converters

LM-GlycomeAtlas

Search Tools

Cross Search Glycan Search Publication Search Programmatic Access

Guidelines

MIRAGE

symplekin scaffold protein

Summary

Gene Symbol

SYMPK

Organism

Homo sapiens (human)

External Links

NCBI Gene

8189

PubChem

8189

Alliance of Genome Resources

HGNC:22935

Annotation

Keyword

3D-structure
Alternative splicing
Cell adhesion
Cell membrane
Cytoskeleton
Isopeptide bond
Nucleus
Phosphoprotein
Reference proteome
Repeat
Tight junction
Ubl conjugation
mRNA processing

Proteins

Displaying 1 entry
UniProt	Protein Name
Q92797

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
mRNA processing	IEA
cell adhesion	IEA
negative regulation of protein binding	IMP	29158257

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA metabolic process [inference]

mRNA processing

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA metabolic process [inference]

mRNA processing

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA metabolic process [inference]

mRNA processing

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA metabolic process [inference]

mRNA processing

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA metabolic process [inference]

mRNA processing

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA metabolic process [inference]

mRNA processing

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA metabolic process [inference]

mRNA processing

cellular process [inference]

cell adhesion

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA metabolic process [inference]

mRNA processing

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA metabolic process [inference]

mRNA processing

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA metabolic process [inference]

mRNA processing

biological regulation [inference]

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of binding [inference]

negative regulation of protein binding

regulation of binding [inference]

regulation of protein binding [inference]

negative regulation of protein binding

negative regulation of binding [inference]

negative regulation of protein binding

Displaying entries **1 - 5** of 10 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
nucleoplasm	TAS
nucleoplasm	IDA	8769423
cytoplasm	IDA	8769423
cytosol	IDA
mRNA cleavage and polyadenylation specificity factor complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

mRNA cleavage factor complex [inference]

mRNA cleavage and polyadenylation specificity factor complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

nuclear body

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

tight junction [inference]

bicellular tight junction

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

ribonucleoprotein granule [inference]

nuclear stress granule

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

ribonucleoprotein granule [inference]

nuclear stress granule

supramolecular complex [inference]

ribonucleoprotein granule [inference]

nuclear stress granule

Displaying 1 entry
GO Term	Evidence Code	PMID
protein binding	IPI	14707147 18288197 18688255 20861839 26496610 32814053 33961781 34819669 35177536

GO Hierarchy

molecular function

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

symplekin

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis

Displaying **all 2** entries
Gene Ontology
mRNA polyadenylation
mRNA processing

Displaying **all 5** entries
InterPro
Armadillo-like helical
Armadillo-type fold
Symplekin C-terminal
Symplekin/Pta1, N-terminal
Symplekin/Pta1

Ortholog

Displaying entries **11 - 20** of 75 in total

« First

‹ Prev

1

2

3

4

5

6

…

Next ›

Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Bos taurus	100337373		BOVIN11346
Callithrix jacchus	100412467		CALJA23571
Ailuropoda melanoleuca	100474335		AILME03210
Sus scrofa	100512609		PIGXX28099
Loxodonta africana	100660841		LOXAF17993
Oreochromis niloticus	100708219		ORENI23232
Cavia porcellus	100714088		CAVPO20473
Otolemur garnettii	100964292		OTOGA03821
Pan paniscus	100983890		PANPA20831
Saimiri boliviensis boliviensis	101052305		SAIBB33040

About Release Notes Help Feedback

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

Logo License Policies Site Map

Contact: support@glycosmos.org

GlyCosmos Portal v4.4.0

Last updated: December 8, 2025