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SCF ubiquitin ligase complex subunit GRR1

Summary

Gene Symbol

GRR1

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

853552

PubChem

853552

Alliance of Genome Resources

SGD:S000003850

Annotation

Keyword

Glucose metabolism
Leucine-rich repeat
Membrane
Phosphoprotein
Reference proteome
Repeat
Ubl conjugation pathway

Proteins

Displaying 1 entry
UniProt	Protein Name
P24814	F-box and leucine-rich repeat protein GRR1 F-box/LRR-repeat protein GRR1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
G1/S transition of mitotic cell cycle
protein polyubiquitination	IMP	16093347
protein polyubiquitination	IGI	9499404
mitotic cell cycle G1 arrest in response to pheromone	IMP	15942932
glucose metabolic process	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination

macromolecule modification [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process [inference]

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

cellular process [inference]

cell cycle process [inference]

cell cycle phase transition [inference]

mitotic cell cycle phase transition [inference]

G1/S transition of mitotic cell cycle

cell cycle G1/S phase transition [inference]

G1/S transition of mitotic cell cycle

mitotic cell cycle process [inference]

mitotic cell cycle phase transition [inference]

G1/S transition of mitotic cell cycle

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

cellular response to organic substance [inference]

cellular response to methylmercury

response to stimulus [inference]

response to stress [inference]

response to oxidative stress [inference]

cellular response to oxidative stress

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

response to chemical [inference]

response to organic substance [inference]

response to methylmercury [inference]

cellular response to methylmercury

cellular response to organic substance [inference]

cellular response to methylmercury

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

cellular response to organic substance [inference]

cellular response to methylmercury

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

cellular response to organic substance [inference]

cellular response to methylmercury

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

regulation of glucose transmembrane transport [inference]

positive regulation of glucose transmembrane transport

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell cycle [inference]

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle G1 arrest in response to pheromone

regulation of cellular process [inference]

regulation of transmembrane transport [inference]

regulation of glucose transmembrane transport [inference]

positive regulation of glucose transmembrane transport

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport

positive regulation of cellular process [inference]

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport

negative regulation of cellular process [inference]

negative regulation of cell cycle [inference]

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle G1 arrest in response to pheromone

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle G1 arrest in response to pheromone

negative regulation of cell cycle [inference]

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle G1 arrest in response to pheromone

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
cellular bud neck contractile ring	IDA	11080155 15775961
nucleus	IDA	11080155
cytoplasm	IDA	11080155
cytoplasm	IBA
membrane	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

ubiquitin ligase complex [inference]

cullin-RING ubiquitin ligase complex [inference]

SCF ubiquitin ligase complex

catalytic complex [inference]

transferase complex [inference]

ubiquitin ligase complex [inference]

cullin-RING ubiquitin ligase complex [inference]

SCF ubiquitin ligase complex

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

contractile ring [inference]

actomyosin contractile ring [inference]

mitotic actomyosin contractile ring [inference]

cellular bud neck contractile ring

Displaying **all 3** entries
GO Term	Evidence Code	PMID
ubiquitin-protein transferase activity	IDA	10213692
protein-macromolecule adaptor activity	IDA	11259599 9346238 9819356
protein-macromolecule adaptor activity	IMP	9819356

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

aminoacyltransferase activity [inference]

ubiquitin-like protein transferase activity [inference]

ubiquitin-protein transferase activity

catalytic activity, acting on a protein [inference]

ubiquitin-like protein transferase activity [inference]

ubiquitin-protein transferase activity

molecular adaptor activity [inference]

protein-macromolecule adaptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

F-box protein

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
Leucine-rich repeat domain superfamily
Leucine-rich repeat, cysteine-containing subtype

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
nucleus	PMID:11080155
cellular bud neck contractile ring	PMID:11080155 PMID:15775961
cytoplasm	PMID:11080155

Ortholog

Displaying **all 6** entries
Species	Gene ID	Alliance of Genome Resources
Danio rerio	23194	ZFIN:ZDB-GENE-061215-122
Caenorhabditis elegans	25827	WB:WBGene00015350
Rattus norvegicus	64839	RGD:1309773
Danio rerio	222235	ZFIN:ZDB-GENE-140106-120
Danio rerio	448987	ZFIN:ZDB-GENE-120709-25
Xenopus tropicalis	853552	Xenbase:XB-GENE-973058

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OrthoDB (Group)

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Acknowledgements