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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
MAP kinase activating death domain
Summary
- Gene Symbol
-
- MADD
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Apoptosis
- Cell membrane
- Cell projection
- Cytoplasm
- Guanine-nucleotide releasing factor
- Intellectual disability
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A0A0MRB5 |
|
| Q8WXG6 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of MAPK cascade | ||
| regulation of Rab protein signal transduction | ||
| cell surface receptor signaling pathway | ||
| regulation of extrinsic apoptotic signaling pathway | ||
| regulation of extrinsic apoptotic signaling pathway via death domain receptors |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| death receptor binding | ||
| guanyl-nucleotide exchange factor activity | ||
| protein kinase activator activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- MAP kinase-activating death domain protein
- Functional Category
-
- G: Carbohydrate transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| regulation of Rab protein signal transduction |
| regulation of apoptotic process |
| InterPro |
|---|
| DENN domain, C-terminal lobe |
| MAP kinase-activating death domain protein |
| Tripartite DENN domain |
| cDENN domain |
| dDENN domain |
| uDENN domain |
Disease
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 32442 | FB:FBgn0030613 | |||
| 94193 | RGD:619922 | RATNO26495 | ||
| 180420 | WB:WBGene00000086 | |||
| 228355 | MGI:2444672 | MOUSE32559 | ||
| 451167 | 9598_0:002e2b | PANTR02800 | ||
| 475982 | CANLF05848 | |||
| 534306 | BOVIN07528 | |||
| 713613 | MACMU09512 | |||
| 100012321 | MONDO26799 | |||
| 100082325 | ORNAN19090 |
