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MIRAGE
cholinergic receptor nicotinic alpha 6 subunit
Summary
- Gene Symbol
-
- CHRNA6
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Disulfide bond
- Glycoprotein
- Ligand-gated ion channel
- Phosphoprotein
- Postsynaptic cell membrane
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q15825 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| signal transduction | ||
| chemical synaptic transmission | ||
| synaptic transmission, cholinergic | ||
| neuromuscular synaptic transmission | ||
| regulation of dopamine secretion |
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| acetylcholine-gated channel complex | ||
| presynaptic membrane | ||
| neuron projection |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| acetylcholine receptor activity | ||
| acetylcholine-gated monoatomic cation-selective channel activity | ||
| acetylcholine-gated monoatomic cation-selective channel activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- acetylcholine receptor subunit
- Functional Category
-
- E: Amino acid transport and metabolism
- T: Signal transduction mechanisms
- X: Mobilome: prophages, transposons
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050742 | nicotine dependence | |
| DOID:1574 | alcohol use disorder | |
| DOID:809 | cocaine abuse |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 472750 | PANTR42482 | ||
| 482836 | CANLF04647 | ||
| 539113 | BOVIN22174 | ||
| 705725 | MACMU43367 | ||
| 100033042 | MONDO09271 | ||
| 100049908 | HORSE25202 | ||
| 100078739 | ORNAN21303 | ||
| 100225640 | TAEGU31431 | ||
| 100355656 | RABIT14329 | ||
| 100399236 | CALJA09796 |
