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Standards Ontologies Notations
cholinergic receptor nicotinic alpha 6 subunit

Summary
Gene Symbol
  • CHRNA6
Organism
Homo sapiens (human)
NCBI Gene
8973
PubChem
8973
Alliance of Genome Resources
Annotation
Keyword
  • Alternative splicing
  • Cell membrane
  • Disulfide bond
  • Glycoprotein
  • Ligand-gated ion channel
  • Phosphoprotein
  • Postsynaptic cell membrane
  • Receptor
  • Reference proteome
  • Signal
  • Transmembrane helix
Proteins
Displaying 1 entry
UniProt Protein Name
Q15825
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 11 in total
GO Term Evidence Code PMID
acetylcholine receptor signaling pathway
synaptic transmission, cholinergic
excitatory postsynaptic potential
ion transmembrane transport
presynaptic modulation of chemical synaptic transmission
GO Hierarchy
Displaying all 3 entries
GO Term Evidence Code PMID
protein binding
acetylcholine receptor activity
acetylcholine-gated monoatomic cation-selective channel activity
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
AcetylCholine Receptor
Functional Category
  • E: Amino acid transport and metabolism
  • T: Signal transduction mechanisms
  • X: Mobilome: prophages, transposons
Displaying all 5 entries
Gene Ontology
excitatory postsynaptic potential
extracellular ligand-gated monoatomic ion channel activity
monoatomic ion channel activity
monoatomic ion transport
regulation of postsynaptic membrane potential
Displaying all 8 entries
InterPro
Neuronal acetylcholine receptor
Neurotransmitter-gated ion-channel ligand-binding domain superfamily
Neurotransmitter-gated ion-channel ligand-binding domain
Neurotransmitter-gated ion-channel transmembrane domain superfamily
Neurotransmitter-gated ion-channel transmembrane domain
Neurotransmitter-gated ion-channel, conserved site
Neurotransmitter-gated ion-channel
Nicotinic acetylcholine receptor
Disease
Disease Ontology
Displaying all 4 entries
DO ID Disease Name Source
DOID:0050742 nicotine dependence
DOID:1574 alcohol use disorder
DOID:3635 congenital myasthenic syndrome
DOID:809 cocaine abuse
Ortholog
Displaying entries 41 - 50 of 79 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
101098219 FELCA08888
101119532 SHEEP13206
101147139 9595_0:00297a GORGO40583
101329586 TURTR14530
101584800 OCTDE09700
101689604 MUSPF03470
101877804 MELUD01232
101938208 CHRPI18774
101954971 ICTTR12331
102122218 MACFA40832
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024