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MIRAGE
CD86 molecule
Summary
- Gene Symbol
-
- CD86
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Adaptive immunity
- Alternative splicing
- Cell membrane
- Disulfide bond
- Glycoprotein
- Host cell receptor for virus entry
- Host-virus interaction
- Immunoglobulin domain
- Reference proteome
- Signal
- Transmembrane helix
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| A8K632 |
|
| A0A0X9R4E0 |
|
| P42081 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| adaptive immune response | ||
| positive regulation of immunoglobulin production | ||
| immune response | ||
| cell surface receptor signaling pathway | ||
| positive regulation of cell population proliferation |
GO Hierarchy
biological process
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
positive regulation of immune system process [inference]
regulation of leukocyte activation [inference]
regulation of immune effector process [inference]
regulation of immune response [inference]
regulation of hemopoiesis [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of metabolic process [inference]
positive regulation of cellular process [inference]
positive regulation of developmental process [inference]
positive regulation of multicellular organismal process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cell differentiation [inference]
positive regulation of developmental process [inference]
regulation of multicellular organismal development [inference]
regulation of cellular process [inference]
regulation of cell adhesion [inference]
regulation of cellular metabolic process [inference]
regulation of cell population proliferation [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
regulation of cell activation [inference]
regulation of leukocyte activation [inference]
positive regulation of cell activation [inference]
regulation of multicellular organismal process [inference]
regulation of cell activation [inference]
regulation of leukocyte activation [inference]
positive regulation of cell activation [inference]
positive regulation of multicellular organismal process [inference]
regulation of multicellular organismal development [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| external side of plasma membrane | ||
| cell surface |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| virus receptor activity | ||
| protein binding | ||
| coreceptor activity | ||
| signaling receptor activity | ||
| receptor ligand activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- CD86
- Functional Category
-
- L: Replication, recombination and repair
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| InterPro |
|---|
| CD80-like, immunoglobulin C2-set |
| Immunoglobulin-like domain superfamily |
| Immunoglobulin-like domain |
| Immunoglobulin-like fold |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1040 | chronic lymphocytic leukemia | |
| DOID:11123 | IgA vasculitis | |
| DOID:2377 | multiple sclerosis | |
| DOID:2841 | asthma | |
| DOID:3083 | chronic obstructive pulmonary disease | |
| DOID:418 | systemic scleroderma | |
| DOID:8924 | autoimmune thrombocytopenic purpura | |
| DOID:9744 | type 1 diabetes mellitus |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 942 | Xenbase:XB-GENE-994998 | ||
| 12524 | Xenbase:XB-GENE-994998 | MOUSE19499 | |
| 56822 | RATNO04224 | ||
| 397441 | PIGXX05569 | ||
| 403764 | CANLF13350 | ||
| 414345 | BOVIN14606 | ||
| 470900 | PANTR31972 | ||
| 493704 | FELCA22377 | ||
| 554318 | SHEEP01430 | ||
| 714390 | MACMU28382 |
