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G00048MO

Summary

GlyTouCan ID: G00048MO
IUPAC Condensed: Fuc(a1-2)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-
Motifs: Leb Lewis b Type 1 LN
Subsumption Level: Fully-defined saccharide
Monoisotopic Mass: 675.26

External Links

GlyGen

G00048MO

ChEBI

59441

PubChem Compound

45480569

PubChem Substance

252279306

CarbBank

609 632 2591 2592 3680 4592 7764 10750 11676 14314 14327 14797 14806 14879 15227 15506 16399 17270 19154 19267 20260 23720 28540 28558 28576 28582 28593 30018 32873 33527 33967 34482 34674 34708 34788 34798 34846 34943 34978 34982 35040 36257 36813 36882 36920 36940 37264 37379 38015 42685 42871 42932 43457 43743 44219 44373 44523 44893 45125 45859 45894 45899 46189 46493 46559 47071 47858 48383 49348 49518 49664 50531 50532

3D Structures

GLYCAM: LFucpa1-2DGalpb1-3[LFucpa1-4]DGlcpNAcb1-OH

GlycoShape

G00048MO

Displaying 1 entry
Archetype	α	β
G93507IP	G92795ML	G00048MO

Organisms

Displaying **all 5** entries
Organisms	Evidence
Oryctolagus cuniculus (rabbit)	GlyTouCan(glycome-db)
Chlorocebus aethiops (grivet)	GlyTouCan(glycome-db)
Helicobacter pylori	GlyTouCan(bcsdb) GlyTouCan(glycome-db)
Mus musculus (house mouse)	GlyTouCan(glycome-db)
Homo sapiens (human)	GlyTouCan(glycome-db)

Taxonomic Hierarchy

root

cellular organisms [inference]

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Euarchontoglires [inference]

Glires (Rodents and rabbits) [inference]

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Lagomorpha [inference]

Leporidae (rabbits and hares) [inference]

Oryctolagus [inference]

Oryctolagus cuniculus (rabbit)

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Catarrhini [inference]

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Cercopithecoidea [inference]

Cercopithecidae (Old World monkeys) [inference]

Cercopithecinae [inference]

Chlorocebus [inference]

Chlorocebus aethiops (grivet)

Bacteria (eubacteria) [inference]

Campylobacterota [inference]

Epsilonproteobacteria [inference]

Campylobacterales [inference]

Helicobacteraceae [inference]

Helicobacter [inference]

Helicobacter pylori

GlycoGene Database (GGDB)

Displaying 1 entry
Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
FUT3	GDP-Fuc	G40696TO	R	G00048MO	R	7721776

Displaying **all 3** entries
Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
FUT5	GDP-Fuc	G40696TO	(CH2)8COOCH3	G00048MO	(CH2)8COOCH3	9079712
FUT3	GDP-Fuc	G40696TO	R	G00048MO	R	7721776
FUT3	GDP-Fuc	G40696TO	(CH2)8COOCH3	G00048MO	(CH2)8COOCH3	9079712

GlycoEpitope

Epitope ID: EP0010

Sequence Descriptors

GlycoCT

RES
1b:b-dglc-HEX-1:5
2s:n-acetyl
3b:b-dgal-HEX-1:5
4b:a-lgal-HEX-1:5|6:d
5b:a-lgal-HEX-1:5|6:d
LIN
1:1d(2+1)2n
2:1o(3+1)3d
3:3o(2+1)4d
4:1o(4+1)5d

WURCS

WURCS=2.0/3,4,3/[a2122h-1b_1-5_2*NCC/3=O][a2112h-1b_1-5][a1221m-1a_1-5]/1-2-3-3/a3-b1_a4-d1_b2-c1

Literature

Displaying entries **1 - 10** of 31 in total

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Last »
PubMed ID	Title	First Author	Publication Date	Source
25428879	Human Noroviruses' Fondness for Histo-Blood Group Antigens	Singh BK	2015 Feb 15	PubChem
24391218	Mannan-Binding Protein, a C-Type Serum Lectin, Recognizes Primary Colorectal Carcinomas through Tumor-Associated Lewis Glycans	Nonaka M	2014 Feb 01	PubChem
22855491	Structural Basis for the Recognition of Lewis Antigens by Genogroup I Norovirus	Kubota T	2012 Oct 15	PubChem
22160312	Helicobacter pylori isolates from Greek children express type 2 and type 1 Lewis and α1,6-glucan antigens in conjunction with a functional type IV secretion system	Altman E	2012 Apr 01	PubChem
23181061	Manipulating the Lewis antigen specificity of the cholesterol-dependent cytolysin lectinolysin	Lawrence SL	2012	PubChem
20008521	Host-dependent Lewis (Le) antigen expression in Helicobacter pylori cells recovered from Leb-transgenic mice	Pohl MA	2009 Dec 14	PubChem
18436591	Analysis of Helicobacter pylori isolates from Chile: occurrence of selective type 1 Lewis b antigen expression in lipopolysaccharide	Altman E	2008 May	PubChem
17386027	A Monoclonal Antibody to Lewis Y/Lewis b Revealing Mimicry of the Histone H1 to Carbohydrate Structures	Christensen PA	2007 Mar 02	PubChem
12213787	Tumor-related expression of alpha1,2fucosylated antigens on colorectal carcinoma cells and its suppression by cell-mediated priming using sugar acceptors for alpha1,2fucosyltransferase	Yazawa S	2002 Sep	GlyGen GlycoEpitope
11443557	Lewis Antigen Expression byHelicobacter pylori	Rasko DA	2001 Aug 01	PubChem

PubAnnotation

Displaying entries **1 - 5** of 10 in total

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Title	Authors	Source	Publication Date	PubMed ID
Structure of a colitose-containing O-specific polysaccharide of the marine bacterium Pseudoalteromonas tetraodonis IAM 14160(T).	Muldoon J Perepelov AV Shashkov AS Gorshkova RP Nazarenko EL Zubkov VA Ivanova EP Knirel YA Savage AV	Carbohydr Res	2001 Jun 22	11423109
Hydroxy protons in conformational study of a Lewis b tetrasaccharide derivative in aqueous solution by NMR spectroscopy.	Bekiroglu S Sandström C Norberg T Kenne L	Carbohydr Res	2000 Sep 22	11072848
Synthesis of the Lewis b hexasaccharide and squarate acid-HSA conjugates thereof with various saccharide loadings.	Chernyak A Oscarson S Turek D	Carbohydr Res	2000 Nov 3	11117314
The human gastric colonizer Helicobacter pylori: a challenge for host-parasite glycobiology.	Karlsson KA	Glycobiology	2000 Aug	10929002
alpha1,2Fucosyltransferase increases resistance to apoptosis of rat colon carcinoma cells.	Goupille C Marionneau S Bureau V Hallouin F Meichenin M Rocher J Le Pendu J	Glycobiology	2000 Apr	10764825

GlyTouCan

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