G36123IU

Summary
GlyTouCan ID
G36123IU
IUPAC Condensed
Neu5Ac(a2-6)GalNAc(a1-
Motifs
Sialyl Tn antigen
Subsumption Level
Fully-defined saccharide
Monoisotopic Mass
512.19
3D Structures
GlycoShape
G36123IU
Displaying 1 entry
Archetype α β
G15807NZ
G36123IU
G73708UL
Organisms
Taxonomic Hierarchy
GlycoGene Database (GGDB)
Displaying all 2 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
ST6GALNAC1 CMP-Neu5Ac
G57321FI
Ser/Thr
G36123IU
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
O-glycan Synthesis
G36123IU
O-glycan Synthesis
Displaying all 5 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
ST8SIA6 CMP-Neu5Ac
G36123IU
Ser/Thr
G25604VV
Ser/Thr
ST6GALNAC4 CMP-Neu5Ac
G57321FI
benzyl
G36123IU
benzyl
ST6GALNAC1 CMP-Neu5Ac
G57321FI
Ser/Thr
G36123IU
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
O-glycan Synthesis
G36123IU
O-glycan Synthesis
ST6GALNAC1 CMP-Neu5Ac
G57321FI
[Ala-Thr(*)-Ala]2-7
G36123IU
[Ala-Thr(*)-Ala]2-7
KEGG BRITE Database
KEGG ID
Enzyme
Reactions
Displaying 1 entry
KEGG Reaction Enzyme Acceptor Product
R05911
GlycoEpitope
Epitope ID
EP0022
Sequence Descriptors
GlycoCT
RES
1b:a-dgal-HEX-1:5
2s:n-acetyl
3b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
4s:n-acetyl
LIN
1:1d(2+1)2n
2:1o(6+2)3d
3:3d(5+1)4n
WURCS
WURCS=2.0/2,2,1/[a2112h-1a_1-5_2*NCC/3=O][Aad21122h-2a_2-6_5*NCC/3=O]/1-2/a6-b2
Literature
Displaying entries 21 - 30 of 135 in total
PubMed ID Title First Author Publication Date Source
15843572 Antibodies against tumor cell glycolipids and proteins, but not mucins, mediate complement-dependent cytotoxicity Ragupathi G 2005 May 01
  • GlyGen
  • GlycoEpitope
15770530 Stable expression of sialyl-Tn antigen in T47-D cells induces a decrease of cell adhesion and an increase of cell migration Julien S 2005 Mar
  • GlyGen
  • GlycoEpitope
15944793 Simple mucin-type cancer associated antigens are pre-cancerous biomarkers during 1,2-dimethylhydrazine-induced rat colon carcinogenesis Berriel E 2005 Jul
  • GlyGen
  • GlycoEpitope
15730515 Epitope recognition of antibodies that define the sialomucin, endolyn (CD164), a negative regulator of haematopoiesis Jorgensen-Tye B 2005 Feb 23
  • GlyGen
  • GlycoEpitope
16120058 Molecular cloning and expression of a human hST8Sia VI (alpha2,8-sialyltransferase) responsible for the synthesis of the diSia motif on O-glycosylproteins Teintenier-Lelièvre M 2005 Dec 06
  • PubChem
15466199 Role of the human ST6GalNAc-I and ST6GalNAc-II in the synthesis of the cancer-associated sialyl-Tn antigen Marcos NT 2004 Oct 01
  • GlyGen
  • GlycoEpitope
15272600 [Clinical usefulness of circulating tumor markers] Ohkura H 2004 Jul
  • GlyGen
  • GlycoEpitope
15536336 Expression of cellular adhesion proteins and abnormal glycoproteins in human aberrant crypt foci Wargovich MJ 2004 Dec
  • GlyGen
  • GlycoEpitope
15539921 Correlation analysis between tumor-associated antigen sialyl-Tn expression and ST6GalNAc I activity in human colon adenocarcinoma Vazquez-Martin C 2004
  • GlyGen
  • GlycoEpitope
12556292 SIALYL-Tn antigen distribution in Helicobacter pylori chronic gastritis in children: an immunohistochemical study Cohen M 2003 Mar-Apr
  • GlyGen
  • GlycoEpitope
PubAnnotation
Displaying entries 1 - 5 of 8 in total
Title Authors Source Publication Date PubMed ID
Organization of the extracellular portion of the macrophage galactose receptor: a trimeric cluster of simple binding sites for N-acetylgalactosamine.
  • Jégouzo SA
  • Quintero-Martínez A
  • Ouyang X
  • dos Santos Á
  • Taylor ME
  • Drickamer K
Glycobiology 2013 Jul 23507965
Use of lectins for probing differentiated human embryonic stem cells for carbohydrates.
  • Wearne KA
  • Winter HC
  • O'Shea K
  • Goldstein IJ
Glycobiology 2006 Oct 16809438
ST6GalNAc I expression in MDA-MB-231 breast cancer cells greatly modifies their O-glycosylation pattern and enhances their tumourigenicity.
  • Julien S
  • Adriaenssens E
  • Ottenberg K
  • Furlan A
  • Courtand G
  • Vercoutter-Edouart AS
  • Hanisch FG
  • Delannoy P
  • Le Bourhis X
Glycobiology 2006 Jan 16135558
Thomsen-Friedenreich antigen expression in gastric carcinomas is associated with MUC1 mucin VNTR polymorphism.
  • Santos-Silva F
  • Fonseca A
  • Caffrey T
  • Carvalho F
  • Mesquita P
  • Reis C
  • Almeida R
  • David L
  • Hollingsworth MA
Glycobiology 2005 May 15604091
Expression of sialyl-Tn antigen in breast cancer cells transfected with the human CMP-Neu5Ac: GalNAc alpha2,6-sialyltransferase (ST6GalNac I) cDNA.
  • Julien S
  • Krzewinski-Recchi MA
  • Harduin-Lepers A
  • Gouyer V
  • Huet G
  • Le Bourhis X
  • Delannoy P
Glycoconj J 2001 Nov-Dec 12820722

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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