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MIRAGE
G36123IU

Summary
GlyTouCan ID
G36123IU
IUPAC Condensed
Neu5Ac(a2-6)GalNAc(a1-
Motifs
Sialyl Tn antigen
Subsumption Level
Fully-defined saccharide
Monoisotopic Mass
512.19
GlyConnect structure
GlyGen
ChEBI
PubChem Compound
PubChem Substance
CarbBank
17 18 8078 8107 14340 29369 31593 33914 33954 34694 34796 34824 34828 34840 34851 34884 35030 35037 35262 35804 35832 35945 37037 37483 38123 38172 38180 38639 38681 39371 41260 41261 41262 41264 41460 41865 42401 42414 42415 42426 42791 43839 43913 43914 43946 43993 44034 44035 44217 44244 44375 44502 44503 44504 45871 45891 46222 46445 46861 47325 47952 48044 48234 48246 48364 48373 48889 49039 49040 49516 49610
3D Structures
GLYCAM
Neup5Aca2-6DGalpNAca1-OH
GlycoShape
G36123IU
Displaying 1 entry
Archetype α β
G15807NZ
G36123IU
G73708UL
Organisms
Displaying entries 1 - 5 of 10 in total
Organisms Evidence
Fasciola hepatica (liver fluke)
Trypanosoma cruzi
Oryctolagus cuniculus (rabbit)
Mesocestoides vogae
Mus musculus (house mouse)
Taxonomic Hierarchy
GlycoGene Database (GGDB)
Displaying all 2 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
ST6GALNAC1 CMP-Neu5Ac
G57321FI
Ser/Thr
G36123IU
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
O-glycan Synthesis
G36123IU
O-glycan Synthesis
Displaying all 5 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
ST8SIA6 CMP-Neu5Ac
G36123IU
Ser/Thr
G25604VV
Ser/Thr
ST6GALNAC4 CMP-Neu5Ac
G57321FI
benzyl
G36123IU
benzyl
ST6GALNAC1 CMP-Neu5Ac
G57321FI
Ser/Thr
G36123IU
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
O-glycan Synthesis
G36123IU
O-glycan Synthesis
ST6GALNAC1 CMP-Neu5Ac
G57321FI
[Ala-Thr(*)-Ala]2-7
G36123IU
[Ala-Thr(*)-Ala]2-7
KEGG BRITE Database
KEGG ID
Enzyme
Reactions
Displaying 1 entry
KEGG Reaction Enzyme Acceptor Product
R05911
Core Protein
Displaying all 6 entries
UniProt ID Protein Name Reference Source
P01588 Erythropoietin
P02724 Glycophorin-A
P15941 Mucin-1
P16150 Leukosialin
Q02817 Mucin-2
Q62635 Mucin-2 (Fragment)
GlycoEpitope
Epitope ID
EP0022
Sequence Descriptors
GlycoCT
RES
1b:a-dgal-HEX-1:5
2s:n-acetyl
3b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
4s:n-acetyl
LIN
1:1d(2+1)2n
2:1o(6+2)3d
3:3d(5+1)4n
WURCS
WURCS=2.0/2,2,1/[a2112h-1a_1-5_2*NCC/3=O][Aad21122h-2a_2-6_5*NCC/3=O]/1-2/a6-b2
Literature
Displaying entries 31 - 40 of 135 in total
PubMed ID Title First Author Publication Date Source
12547345 Mucin-type O-glycosylation in Fasciola hepatica: characterisation of carcinoma-associated Tn and sialyl-Tn antigens and evaluation of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase activity Freire T 2003 Jan
  • GlyGen
  • GlycoEpitope
14652017 Sialyl-Tn antigen expression and O-linked GalNAc-Thr synthesis by Trypanosoma cruzi Freire T 2003 Dec 26
  • GlyGen
  • GlycoEpitope
12000758 Recombinant MUC1 probe authentically reflects cell-specific O-glycosylation profiles of endogenous breast cancer mucin. High density and prevalent core 2-based glycosylation Muller S 2002 Jul 19
  • GlyGen
12017332 Predictive factors for preoperative serum levels of sialy Lewis(x), sialyl Lewis(a) and sialyl Tn antigens in gastric cancer patients Nakagoe T 2002 Jan
  • GlyGen
  • GlycoEpitope
12460925 Vascular endothelial growth factor secretion by tumor-infiltrating macrophages essentially supports tumor angiogenesis, and IgG immune complexes potentiate the process Barbera-Guillem E 2002 Dec 01
  • GlyGen
  • GlycoEpitope
12820721 A rat model to study the role of STn antigen in colon cancer Ogata S 2001 Nov
  • GlyGen
  • GlycoEpitope
12820722 Expression of sialyl-Tn antigen in breast cancer cells transfected with the human CMP-Neu5Ac: GalNAc alpha2,6-sialyltransferase (ST6GalNac I) cDNA Julien S 2001 Nov
  • GlyGen
  • GlycoEpitope
11501845 Expression of mucin-associated carbohydrate core antigens in esophageal squamous cell carcinomas Flucke U 2001 May-Jun
  • GlyGen
  • GlycoEpitope
11291879 Circulating sialyl Lewis x , sialyl Lewis a , and sialyl Tn antigens in colorectal cancer patients: multivariate analysis of predictive factors for serum antigen levels Nakagoe T 2001 Mar
  • GlyGen
  • GlycoEpitope
11396208 Immunohistochemical expression of T, Tn and sialyl-Tn antigens and clinical outcome in human breast carcinoma Imai J 2001 Mar-Apr
  • GlyGen
  • GlycoEpitope
PubAnnotation
Displaying entries 1 - 5 of 8 in total
Title Authors Source Publication Date PubMed ID
Organization of the extracellular portion of the macrophage galactose receptor: a trimeric cluster of simple binding sites for N-acetylgalactosamine.
  • Jégouzo SA
  • Quintero-Martínez A
  • Ouyang X
  • dos Santos Á
  • Taylor ME
  • Drickamer K
 Glycobiology 2013 Jul 23507965
Use of lectins for probing differentiated human embryonic stem cells for carbohydrates.
  • Wearne KA
  • Winter HC
  • O'Shea K
  • Goldstein IJ
 Glycobiology 2006 Oct 16809438
ST6GalNAc I expression in MDA-MB-231 breast cancer cells greatly modifies their O-glycosylation pattern and enhances their tumourigenicity.
  • Julien S
  • Adriaenssens E
  • Ottenberg K
  • Furlan A
  • Courtand G
  • Vercoutter-Edouart AS
  • Hanisch FG
  • Delannoy P
  • Le Bourhis X
 Glycobiology 2006 Jan 16135558
Thomsen-Friedenreich antigen expression in gastric carcinomas is associated with MUC1 mucin VNTR polymorphism.
  • Santos-Silva F
  • Fonseca A
  • Caffrey T
  • Carvalho F
  • Mesquita P
  • Reis C
  • Almeida R
  • David L
  • Hollingsworth MA
 Glycobiology 2005 May 15604091
Expression of sialyl-Tn antigen in breast cancer cells transfected with the human CMP-Neu5Ac: GalNAc alpha2,6-sialyltransferase (ST6GalNac I) cDNA.
  • Julien S
  • Krzewinski-Recchi MA
  • Harduin-Lepers A
  • Gouyer V
  • Huet G
  • Le Bourhis X
  • Delannoy P
 Glycoconj J 2001 Nov-Dec 12820722
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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